Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50008441
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM577(VX-478 | 141W94 | APV | BDBM50215393 | CHEMBL116 |...)
Affinity DataKi: <0.100nMAssay Description:Binding affinity to HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073365((S)-2-(3-{(R)-3-[Cyclopentylmethyl-(4-methoxy-phen...)
Affinity DataKi:  7nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073364({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  15nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073353({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  17nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073346(N-{(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulf...)
Affinity DataKi:  20nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073350({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  20nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073360(N-[(S)-3-(3-Benzyl-1-phenethyl-ureido)-2-hydroxy-p...)
Affinity DataKi:  22nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073356(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  27nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073359(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  29nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073347({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  38nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073340({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  38nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073366({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  40nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073362(N-Cyclopentylmethyl-N-{(S)-2-hydroxy-3-[3-((1S,2R)...)
Affinity DataKi:  43nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073354({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  50nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073357({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  65nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073363(N-{(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulf...)
Affinity DataKi:  66nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073341(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  76nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073348({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  104nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073339({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  125nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073355({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  173nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073351({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  200nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073352(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  220nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073338({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  300nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073358(Benzyl-{(S)-3-[cyclopentylmethyl-(4-methoxy-benzen...)
Affinity DataKi:  600nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073361(1N-[3-cyclopentylmethyl(4-methoxyphenyl)sulfonamid...)
Affinity DataKi:  680nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073349({(S)-3-[Cyclopentylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073337(N-[(S)-3-(3-tert-Butyl-1-phenethyl-ureido)-2-hydro...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073342(N-Cyclopentylmethyl-N-[(S)-2-hydroxy-3-(3-methyl-1...)
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073336(N-Cyclopentylmethyl-N-[(S)-2-hydroxy-3-(3-isopropy...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073345(N-Cyclopentylmethyl-N-[(S)-2-hydroxy-3-(3-indan-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073344(N-Cyclopentylmethyl-N-{(S)-2-hydroxy-3-[3-(3-metho...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073343(N-Cyclopentylmethyl-N-[(S)-2-hydroxy-3-(1-phenethy...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity against HIV-1 protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed