Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50008438
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM1676((4R,5S,6S,7R)-1,3,4,7-tetrabenzyl-5,6-dihydroxy-1,...)
Affinity DataKi:  3.60nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM1682(CHEMBL120610 | (4R,5S,6R,7R)-Hexahydro-5,6-dihydro...)
Affinity DataKi:  6nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073327((1S,2R,3S,4R,8R,9R)-4-Benzyl-9-benzyloxy-2,3-dihyd...)
Affinity DataKi:  9nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073328((1S,2R,3S,4R,8R,9R)-4,5-Dibenzyl-9-benzyloxy-2,3-d...)
Affinity DataKi:  750nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM1678((4R,5R,6R,7R)-1,3,4,7-tetrabenzyl-5,6-dihydroxy-1,...)
Affinity DataKi:  1.35E+3nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073329((2R,3S,4R)-4-Benzyl-2,3-dihydroxy-5-(1H-indazol-5-...)
Affinity DataKi:  2.30E+3nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073330((2R,3S,4R)-4,5-Dibenzyl-2,3-dihydroxy-5,7-diaza-tr...)
Affinity DataKi:  2.40E+3nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073325((2R,3R,4R)-4,5-Dibenzyl-2,3-dihydroxy-5,7-diaza-tr...)
Affinity DataKi:  6.30E+3nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073326((2R,3R,4R)-4-Benzyl-2,3-dihydroxy-5,7-diaza-tricyc...)
Affinity DataKi:  2.10E+4nMAssay Description:Compound was tested for the inhibition of HIV-1 protease by assaying the cleavage of a fluorescent peptide using HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed