Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50034971
LigandPNGBDBM50072639((S)-2-(2-{[(S)-2-((R)-2-Amino-3-mercapto-propylami...)
Affinity DataIC50: 0.123nMAssay Description:Inhibition of [3H]- FPP incorporation into recombinant Ha-Ras by farnesyl transferase at 10 pMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50366557(CHEMBL1790748)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [3H]- FPP incorporation into recombinant Ha-Ras by farnesyl transferase at 10 pMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072626(2-[2-({2-[2-(4-Cyano-benzylsulfanyl)-acetylamino]-...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072647((S)-2-[2-({(S)-3-Methyl-2-[2-(4-nitro-benzylsulfan...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072645((S)-2-[2-({(S)-3-Methyl-2-[2-(4-methyl-benzylsulfa...)
Affinity DataIC50: 14nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072633((S)-2-[2-({(S)-2-[2-(4-Methanesulfonyl-benzylsulfa...)
Affinity DataIC50: 16nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072628((S)-2-[2-({(S)-3-Methyl-2-[2-(pyridin-4-ylsulfanyl...)
Affinity DataIC50: 17nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072644((S)-2-[2-({(S)-2-[2-(4-Methoxy-benzylsulfanyl)-ace...)
Affinity DataIC50: 17nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072623((S)-2-[2-({(S)-3-Methyl-2-[4-(4-nitro-phenyl)-buty...)
Affinity DataIC50: 19nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072629((S)-2-[2-({(S)-3-Methyl-2-[2-(3-nitro-benzylsulfan...)
Affinity DataIC50: 23nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072635((S)-2-[2-({(S)-2-[2-(Biphenyl-4-ylmethylsulfanyl)-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072643((S)-2-[2-({(S)-2-[(1H-Imidazol-4-ylmethyl)-amino]-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072648((S)-2-(2-{[(S)-2-(2-Benzylsulfanyl-acetylamino)-3-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072649((S)-4-Methylsulfanyl-2-[2-({(S)-3-methyl-2-[2-(4-t...)
Affinity DataIC50: 37nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072627((S)-2-(2-{[(S)-3-Methyl-2-(2-phenylsulfanyl-acetyl...)
Affinity DataIC50: 51nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072624((S)-2-[2-({(S)-2-[2-(Acetyl-benzyl-amino)-acetylam...)
Affinity DataIC50: 70nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072641((S)-2-[2-({(S)-3-Methyl-2-[2-(2-nitro-benzylsulfan...)
Affinity DataIC50: 86nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072646((S)-2-(2-{[(S)-3-Methyl-2-(2-phenethylsulfanyl-ace...)
Affinity DataIC50: 120nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072631((S)-2-(2-{[(S)-3-Methyl-2-(2-phenylmethanesulfinyl...)
Affinity DataIC50: 160nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072630((S)-2-(2-{[(S)-2-(2-Benzylamino-acetylamino)-3-met...)
Affinity DataIC50: 190nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072636((S)-2-(2-{[(S)-3-Methyl-2-(5-phenyl-pentanoylamino...)
Affinity DataIC50: 230nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072634((S)-2-(2-{[(S)-2-(2-Benzyloxy-acetylamino)-3-methy...)
Affinity DataIC50: 230nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072625((S)-2-[2-({(S)-3-Methyl-2-[2-(pyridin-4-ylmethylsu...)
Affinity DataIC50: 230nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072638((S)-2-[2-({(S)-2-[2-(Benzyl-tert-butoxycarbonyl-am...)
Affinity DataIC50: 260nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072640((S)-2-(2-{[(S)-3-Methyl-2-(2-phenylmethanesulfonyl...)
Affinity DataIC50: 310nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072637((S)-2-[2-(Benzyl-{(S)-3-methyl-2-[2-(1H-[1,2,4]tri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072632((S)-2-[2-({(S)-2-[2-(1H-Benzoimidazol-2-ylsulfanyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50072642((S)-2-[2-({(S)-2-[2-(5-Amino-[1,3,4]thiadiazol-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed