Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50008188
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071342(4-Chloro-N-[4-(1H-imidazol-4-yl)-butyl]-N-(4-imida...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071343(4-Chloro-N-[4-(1H-imidazol-4-yl)-butyl]-N-methyl-b...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071348(4-tert-Butyl-N-[5-(1H-imidazol-4-yl)-pentyl]-benze...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071340(N-[5-(1H-Imidazol-4-yl)-pentyl]-4-nitro-benzenesul...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071352(N-[4-(1H-Imidazol-4-yl)-butyl]-C-phenyl-methanesul...)
Affinity DataKi:  6nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071339(N-[4-(1H-Imidazol-4-yl)-butyl]-4-trifluoromethoxy-...)
Affinity DataKi:  7nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071358(3-Chloro-N-[4-(1H-imidazol-4-yl)-butyl]-benzenesul...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071346(4-Chloro-N-[4-(1H-imidazol-4-yl)-butyl]-benzenesul...)
Affinity DataKi:  9nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071344(N-[4-(1H-Imidazol-4-yl)-butyl]-4-trifluoromethyl-b...)
Affinity DataKi:  10nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071354(N-[4-(1H-Imidazol-4-yl)-butyl]-benzenesulfonamide ...)
Affinity DataKi:  11nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071336(4-Chloro-N-[5-(1H-imidazol-4-yl)-pentyl]-benzenesu...)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071351(N-[4-(1H-Imidazol-4-yl)-butyl]-4-methyl-benzenesul...)
Affinity DataKi:  17nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071337(N-[4-(1H-Imidazol-4-yl)-butyl]-4-nitro-benzenesulf...)
Affinity DataKi:  17nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071356(4-tert-Butyl-N-[4-(1H-imidazol-4-yl)-butyl]-benzen...)
Affinity DataKi:  17nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071347(4-Fluoro-N-[4-(1H-imidazol-4-yl)-butyl]-benzenesul...)
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071338(Propane-2-sulfonic acid [4-(1H-imidazol-4-yl)-buty...)
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071361(N-[5-(1H-Imidazol-4-yl)-pentyl]-4-trifluoromethoxy...)
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071359(4-Chloro-N-(4-chloro-benzyl)-N-[4-(1H-imidazol-4-y...)
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071355(N-[5-(1H-Imidazol-4-yl)-pentyl]-benzenesulfonamide...)
Affinity DataKi:  25nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071363(N-[4-(1H-Imidazol-4-yl)-butyl]-C-(2-nitro-phenyl)-...)
Affinity DataKi:  42nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071350(1-[4-(1H-Imidazol-4-yl)-butylsulfamoyl]-3-methyl-3...)
Affinity DataKi:  43nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071349(Thiophene-2-sulfonic acid [4-(1H-imidazol-4-yl)-bu...)
Affinity DataKi:  45nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071353(4-tert-Butyl-N-[3-(1H-imidazol-4-yl)-propyl]-benze...)
Affinity DataKi:  46nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071362(N-[4-(1H-Imidazol-4-yl)-butyl]-4-methoxy-benzenesu...)
Affinity DataKi:  51nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071357(N-[3-(1H-Imidazol-4-yl)-propyl]-4-nitro-benzenesul...)
Affinity DataKi:  93nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071360(4-Amino-N-[4-(1H-imidazol-4-yl)-butyl]-benzenesulf...)
Affinity DataKi:  99nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071345(4-Chloro-N-[3-(1H-imidazol-4-yl)-propyl]-benzenesu...)
Affinity DataKi:  380nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071341(Thiophene-2-sulfonic acid [3-(1H-imidazol-4-yl)-pr...)
Affinity DataKi:  550nMAssay Description:Inhibition of [3H]Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed