Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50034936
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070546(CHEMBL38763 | SR 140333 | 1-(2-{(S)-3-(3,4-Dichlor...)
Affinity DataIC50: 0.0190nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070548(1-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(3-isopropoxy-p...)
Affinity DataIC50: 0.310nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070554(1'-(2-{3-(3,4-dichlorophenyl)-1-[2-(3-isopropoxyph...)
Affinity DataIC50: 1.90nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070554(1'-(2-{3-(3,4-dichlorophenyl)-1-[2-(3-isopropoxyph...)
Affinity DataIC50: 1.90nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070558(1-(3-(3,4-dichlorophenyl)-3-{2-[1'-methylspiro[1,2...)
Affinity DataIC50: 2nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070552(1-(3-(3,4-dichlorophenyl)-3-{2-[1'-ethylspiro[1,2,...)
Affinity DataIC50: 4.80nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070557(piperidine analogue | CHEMBL38030)
Affinity DataIC50: 6.30nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070550(1-[3-{2-[1'-benzylspiro[1,2,3,4-tetrahydroisoquino...)
Affinity DataIC50: 16nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366500(CHEMBL1201933)
Affinity DataIC50: 16nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070555(piperidine analogue | CHEMBL38624)
Affinity DataIC50: 18nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070556(1-{3-(3,4-Dichloro-phenyl)-3-[2-(3,4-dihydro-2H-sp...)
Affinity DataIC50: 31nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070551(1'-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(3-isopropoxy-...)
Affinity DataIC50: 54nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070549(YM-35384 | N-[2-(3,4-Dichloro-phenyl)-4-(3,4-dihyd...)
Affinity DataIC50: 58nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366499(CHEMBL1794935)
Affinity DataIC50: 105nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSubstance-P receptor(Guinea pig)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070545(1'-[3-(3,4-dichlorophenyl)-4-methyl(phenyl)carboxa...)
Affinity DataIC50: 710nMAssay Description:Neurokinin (NK1) receptor antagonistic activity was evaluated.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed