Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50008070
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070457((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-methyl-N*1*-((S)...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070457((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-methyl-N*1*-((S)...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070453(BB-1101 | (2R,3S)-2-Allyl-N*1*-hydroxy-3-isobutyl-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070453(BB-1101 | (2R,3S)-2-Allyl-N*1*-hydroxy-3-isobutyl-...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070455((R)-N*1*-Hydroxy-3-isobutyl-2,2-dimethyl-N*4*-((S)...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070452((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070452((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070460((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070460((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070461((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcar...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070462((2S,3R)-2-Allyl-N*4*-{(S)-2-cyclohexyl-1-[2-(4-sul...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070455((R)-N*1*-Hydroxy-3-isobutyl-2,2-dimethyl-N*4*-((S)...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070453(BB-1101 | (2R,3S)-2-Allyl-N*1*-hydroxy-3-isobutyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070462((2S,3R)-2-Allyl-N*4*-{(S)-2-cyclohexyl-1-[2-(4-sul...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070462((2S,3R)-2-Allyl-N*4*-{(S)-2-cyclohexyl-1-[2-(4-sul...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070460((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070463((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070463((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070454(1-[(R)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phenyl-...)
Affinity DataIC50: 37nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070454(1-[(R)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phenyl-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070461((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcar...)
Affinity DataIC50: 50nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070457((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-methyl-N*1*-((S)...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070459((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 52nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070456((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070463((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50: 59nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070451((2S,3R)-2-Allyl-N*4*-((S)-2-cyclohexyl-1-phenethyl...)
Affinity DataIC50: 64nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070459((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 66nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070456((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 91nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070461((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-phenylcar...)
Affinity DataIC50: 95nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070451((2S,3R)-2-Allyl-N*4*-((S)-2-cyclohexyl-1-phenethyl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070458((R)-2,2-Diallyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070456((2S,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 120nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070451((2S,3R)-2-Allyl-N*4*-((S)-2-cyclohexyl-1-phenethyl...)
Affinity DataIC50: 160nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070455((R)-N*1*-Hydroxy-3-isobutyl-2,2-dimethyl-N*4*-((S)...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070454(1-[(R)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phenyl-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070459((2R,3R)-2-Allyl-N*1*-hydroxy-3-isobutyl-2-methyl-N...)
Affinity DataIC50: 420nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070452((2S,3R)-2-Allyl-N*4*-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50: 480nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070458((R)-2,2-Diallyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50: 550nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50070458((R)-2,2-Diallyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed