Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50007983
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM22904(CHEMBL268229 | Alpha-Methylhistane-R | (2R)-1-(1H-...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069825(4-Pyrrolidin-3-yl-1H-imidazole | CHEMBL79983)
Affinity DataKi:  2nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069816(SCH-50971 | 4-((3R,4R)-4-Methyl-pyrrolidin-3-yl)-1...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069823(4-((3S,4R)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole ...)
Affinity DataKi:  3nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50034708(4-((2R,3S)-2-Methyl-pyrrolidin-3-yl)-1H-imidazole ...)
Affinity DataKi:  3nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069822(4-((3S,4S)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole ...)
Affinity DataKi:  5nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069818(4-((2R,3S)-2-Methyl-azetidin-3-yl)-1H-imidazole | ...)
Affinity DataKi:  7nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069819(4-((2S,3S)-2-Methyl-pyrrolidin-3-yl)-1H-imidazole ...)
Affinity DataKi:  59nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069817(4-((3S,5S)-5-Methyl-pyrrolidin-3-yl)-1H-imidazole ...)
Affinity DataKi:  76nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069820(4-((2R,3S)-2-Ethyl-pyrrolidin-3-yl)-1H-imidazole |...)
Affinity DataKi:  150nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069815(4-((S)-3-Methyl-pyrrolidin-3-yl)-1H-imidazole | CH...)
Affinity DataKi:  170nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069824((2R,3S)-3-(1H-Imidazol-4-yl)-2-methyl-piperidine |...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069821(4-((2R,3S)-2-Benzyl-pyrrolidin-3-yl)-1H-imidazole ...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50069816(SCH-50971 | 4-((3R,4R)-4-Methyl-pyrrolidin-3-yl)-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to H-1 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine ligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM22904(CHEMBL268229 | Alpha-Methylhistane-R | (2R)-1-(1H-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to H-1 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine ligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed