Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50007964
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065041(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065012(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022279(CL-277082 | 3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dime...)
Affinity DataIC50: 33nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065002(1-(4-Dimethylamino-benzyl)-3-(6-methyl-2,4-bis-met...)
Affinity DataIC50: 72nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065044(FR-186054 | 1-Benzyl-3-(6-methyl-2,4-bis-methylsul...)
Affinity DataIC50: 99nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065058(1-(4-Methoxy-benzyl)-3-(6-methyl-2,4-bis-methylsul...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065057(1-(4-Fluoro-benzyl)-3-(6-methyl-2,4-bis-methylsulf...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed