Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50007925
Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50069315(C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-[4-(...)
Affinity DataEC50:  0.580nMAssay Description:Effective concentration determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor stably transfec...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataEC50:  38nMAssay Description:Effective concentration determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor stably transfec...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataEC50:  16nMAssay Description:Effective concentration determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor stably transfec...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50069315(C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-[4-(...)
Affinity DataKi:  0.640nMAssay Description:Effective concentration determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor stably transfec...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKi:  0.760nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1D receptor using [3H]5-CT radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50069315(C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-[4-(...)
Affinity DataKi:  0.890nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1D receptor using [3H]5-CT radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKi:  4.20nMAssay Description:Effective concentration determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor stably transfec...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKi:  8.60nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1D receptor using [3H]5-CT radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50069315(C-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-[4-(...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKi:  19nMAssay Description:Effective concentration determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor stably transfec...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKi:  124nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKi:  407nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed