Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50007871
TargetSqualene synthase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038096((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50: 12nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058945((1S,2S,3S,4S)-3,4-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50: 37nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068843((1S,2S,3S,5S)-3,5-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50: 170nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068845((1S,2S,3S,5R)-1-Carboxymethyl-3,5-bis-[(4-phenoxy-...)
Affinity DataIC50: 240nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068842((1S,2S,3S,5R)-3,5-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50: 580nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068844((1R,2R,3S,4S)-2,4-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50: 2.90E+3nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068846((2R,3R,4S,5S)-4,5-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068841((1S,3R,4S,5R)-4,5-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50: 9.10E+3nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed