Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50007672
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50066414(Benzhydryl-{2-[1-(4-fluoro-benzyl)-piperidin-4-yl]...)
Affinity DataIC50: 9.40nMAssay Description:IC50 value was evaluated using [3H]WIN-35428 (radioligand) on Dopamine transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50049365(1-benzyl-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)pi...)
Affinity DataIC50: 9.70nMAssay Description:IC50 value was evaluated using [3H]WIN-35428 (radioligand) on Dopamine transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 17.2nMAssay Description:IC50 value was evaluated using [3H]WIN-35428 (radioligand) on Dopamine transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 19.3nMAssay Description:IC50 value was evaluated using [3H]WIN-35428 (radioligand) on Dopamine transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 26nMAssay Description:Affinity was evaluated using [3H]DA (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50066414(Benzhydryl-{2-[1-(4-fluoro-benzyl)-piperidin-4-yl]...)
Affinity DataIC50: 30nMAssay Description:Affinity was evaluated using [3H]WIN-35428 (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50066414(Benzhydryl-{2-[1-(4-fluoro-benzyl)-piperidin-4-yl]...)
Affinity DataIC50: 32nMAssay Description:Affinity was evaluated using [3H]DA (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50066416([2-(1-Benzyl-piperidin-4-yl)-ethyl]-[bis-(4-fluoro...)
Affinity DataIC50: 33nMAssay Description:Affinity was evaluated using [3H]WIN-35428 (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50049365(1-benzyl-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)pi...)
Affinity DataIC50: 35nMAssay Description:Affinity was evaluated using [3H]WIN-35428 (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 37.6nMAssay Description:Affinity was evaluated using [3H]WIN-35428 (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 43nMAssay Description:Affinity was evaluated using [3H]WIN-35428 (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50066416([2-(1-Benzyl-piperidin-4-yl)-ethyl]-[bis-(4-fluoro...)
Affinity DataIC50: 58nMAssay Description:Affinity was evaluated using [3H]DA (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 87nMAssay Description:IC50 value was evaluated using [3H]citalopram (radioligand) on serotonin transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50049365(1-benzyl-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)pi...)
Affinity DataIC50: 198nMAssay Description:IC50 value was evaluated using [3H]citalopram (radioligand) on serotonin transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50066414(Benzhydryl-{2-[1-(4-fluoro-benzyl)-piperidin-4-yl]...)
Affinity DataIC50: 585nMAssay Description:IC50 value was evaluated using [3H]citalopram (radioligand) on serotonin transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 741nMAssay Description:Affinity was evaluated using [3H]citalopram (radioligand) on human serotonin transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 1.92E+3nMAssay Description:IC50 value was evaluated using [3H]citalopram (radioligand) on serotonin transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50066415(N-Benzhydryl-2-[1-(4-fluoro-benzyl)-piperidin-4-yl...)
Affinity DataIC50: 3.21E+3nMAssay Description:Affinity was evaluated using [3H]WIN-35428 (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50066414(Benzhydryl-{2-[1-(4-fluoro-benzyl)-piperidin-4-yl]...)
Affinity DataIC50: 5.85E+3nMAssay Description:Affinity was evaluated using [3H]citalopram (radioligand) on human serotonin transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50066416([2-(1-Benzyl-piperidin-4-yl)-ethyl]-[bis-(4-fluoro...)
Affinity DataIC50: 1.07E+4nMAssay Description:Affinity was evaluated using [3H]citalopram (radioligand) on human serotonin transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50066415(N-Benzhydryl-2-[1-(4-fluoro-benzyl)-piperidin-4-yl...)
Affinity DataIC50: 4.92E+4nMAssay Description:Affinity was evaluated using [3H]citalopram (radioligand) on human serotonin transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed