Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50036636
TargetDelta-type opioid receptor(Mouse)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065856(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Affinity DataIC50: 3.00E+3nMAssay Description:Partial agonist activity expressed as inhibition of contraction of mouse vas deferens (MVD) smooth muscle at 1 uM conc.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065862(22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065854(22-cyclopropylmethyl-9-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  0.610nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065854(22-cyclopropylmethyl-9-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065857(7-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065862(22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065858(9-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065858(9-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065863(22-cyclopropylmethyl-7-[2-(2-pyridyl)-(E)-1-etheny...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065863(22-cyclopropylmethyl-7-[2-(2-pyridyl)-(E)-1-etheny...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065857(7-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065856(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065864(22-cyclopropylmethyl-7-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065852(8-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065856(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065852(8-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065855(22-cyclopropylmethyl-8-phenyl-14-oxa-11,22-diazahe...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065857(7-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065859(6-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065861(22-cyclopropylmethyl-7-phenyl-14-oxa-11,22-diazahe...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065859(6-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065863(22-cyclopropylmethyl-7-[2-(2-pyridyl)-(E)-1-etheny...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065864(22-cyclopropylmethyl-7-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065855(22-cyclopropylmethyl-8-phenyl-14-oxa-11,22-diazahe...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065854(22-cyclopropylmethyl-9-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]OXY from Opioid receptor kappa 2b of guinea pig brain membranes (pretreated with BIT(mu) and FIT(delta) and in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065863(22-cyclopropylmethyl-7-[2-(2-pyridyl)-(E)-1-etheny...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranes (pretreated with BIT and FIT to block mu and delta sites)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065863(22-cyclopropylmethyl-7-[2-(2-pyridyl)-(E)-1-etheny...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]OXY from Opioid receptor kappa 2b of guinea pig brain membranes (pretreated with BIT(mu) and FIT(delta) and in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065861(22-cyclopropylmethyl-7-phenyl-14-oxa-11,22-diazahe...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]DADLE from morphine-insensitive Opioid receptor delta 1 (presence of 50 nM morphine) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranes (pretreated with BIT and FIT to block mu and delta sites)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065854(22-cyclopropylmethyl-9-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranes (pretreated with BIT and FIT to block mu and delta sites)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065854(22-cyclopropylmethyl-9-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065862(22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065853(22-cyclopropylmethyl-6-phenyl-14-oxa-11,22-diazahe...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065854(22-cyclopropylmethyl-9-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  57nMAssay Description:Displacement of [125I]OXY from Opioid receptor kappa 2b of guinea pig brain membranes (pretreated with BIT(mu) and FIT(delta) and in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065851(22-cyclopropylmethyl-6-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1 of rat brain membranes (DAMGO quenching mu receptor)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065858(9-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065859(6-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065864(22-cyclopropylmethyl-7-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranes (pretreated with BIT and FIT to block mu and delta sites)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065863(22-cyclopropylmethyl-7-[2-(2-pyridyl)-(E)-1-etheny...)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065857(7-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065857(7-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranes (pretreated with BIT and FIT to block mu and delta sites)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065857(7-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  86nMAssay Description:Displacement of [125I]OXY from Opioid receptor kappa 2b of guinea pig brain membranes (pretreated with BIT(mu) and FIT(delta) and in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065856(22-cyclopropylmethyl-8-phenoxy-14-oxa-11,22-diazah...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]DADLE from morphine-sensitive Opioid receptor delta 1 (presence of 300 nM DELT-II) of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065862(22-cyclopropylmethyl-9-phenyl-14-oxa-11,22-diazahe...)
Affinity DataKi:  90nMAssay Description:Displacement of [125I]OXY from Opioid receptor kappa 2b of guinea pig brain membranes (pretreated with BIT(mu) and FIT(delta) and in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50065859(6-benzyloxy-22-cyclopropylmethyl-14-oxa-11,22-diaz...)
Affinity DataKi:  109nMAssay Description:Displacement of [125I]OXY from Opioid receptor kappa 2b of guinea pig brain membranes (pretreated with BIT(mu) and FIT(delta) and in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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