Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50036614
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082395((3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 3nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50082395((3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50147851((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 17nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50147851((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...)
Affinity DataIC50: 23nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM86699(4-ARA-127)
Affinity DataIC50: 24.8nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099288(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataIC50: 35nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50454928(CHEMBL2115481)
Affinity DataIC50: 45nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50454929(CHEMBL2115080)
Affinity DataIC50: 49nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50454928(CHEMBL2115481)
Affinity DataIC50: 63nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50454929(CHEMBL2115080)
Affinity DataIC50: 75nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM86699(4-ARA-127)
Affinity DataIC50: 85.2nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 102nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50178672((3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidi...)
Affinity DataIC50: 195nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099288(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataIC50: 197nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 239nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064495([(R)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-yl]-...)
Affinity DataIC50: 442nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50147844(Acetic acid (3R,4S)-4-(4-chloro-phenyl)-1-methyl-p...)
Affinity DataIC50: 461nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50178672((3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidi...)
Affinity DataIC50: 653nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064498((S)-1-Methyl-4-phenyl-piperidine-3-carboxylic acid...)
Affinity DataIC50: 769nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064500(Acetic acid (R)-4-(4-chloro-phenyl)-1-methyl-piper...)
Affinity DataIC50: 928nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099296(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataIC50: 1.36E+3nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064500(Acetic acid (R)-4-(4-chloro-phenyl)-1-methyl-piper...)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099296(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataIC50: 5.09E+3nMAssay Description:Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed