Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50007530
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-met...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of MMP-9 (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-met...)
Affinity DataKi:  0.870nMAssay Description:Inhibition of MMP-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064341(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of MMP-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064341(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of MMP-9 (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-met...)
Affinity DataKi:  1.93nMAssay Description:Inhibition of MMP-3 (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064339((9S,12R,13S)-12-Isobutyl-3,11-dioxo-1-oxa-4,10-dia...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of MMP-9 (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064339((9S,12R,13S)-12-Isobutyl-3,11-dioxo-1-oxa-4,10-dia...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of MMP-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064339((9S,12R,13S)-12-Isobutyl-3,11-dioxo-1-oxa-4,10-dia...)
Affinity DataKi:  24.1nMAssay Description:Inhibition of MMP-3 (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064341(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)
Affinity DataKi:  32.7nMAssay Description:Inhibition of MMP-3 (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed