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Found
119
Enz. Inhib. hit(s) with all data for entry = 5144
Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM22416
(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
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Affinity Data
Ki: 0.130nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM77970
(CLOMIPRAMINE HYDROCHLORIDE | CHLORIMIPRAMINE | 3-(...)
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Affinity Data
Ki: 0.280nM
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Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82217
([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
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Affinity Data
Ki: 0.290nM
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CHEMBL
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PC sid
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM30130
(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
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Affinity Data
Ki: 0.810nM
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Target Info
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ChEBI
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Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
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Affinity Data
Ki: 0.830nM
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Date in BDB:
3/3/2012
Entry Details
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PubMed
PDB
3D Structure (crystal)
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM25870
(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
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Affinity Data
Ki: 1.16nM
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Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
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Affinity Data
Ki: 1.40nM
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Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50176062
(3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-...)
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Affinity Data
Ki: 1.41nM
More data for this Ligand-Target Pair
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Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
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PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50254790
(NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine)
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Affinity Data
Ki: 1.47nM
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ChEBI
CHEMBL
PC cid
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50022784
(Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine(tomoxe...)
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Affinity Data
Ki: 2.03nM
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50028091
((1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan...)
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Affinity Data
Ki: 2.20nM
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Date in BDB:
3/3/2012
Entry Details
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PubMed
PDB
3D Structure (crystal)
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50028066
(CHEMBL40733 | Desmethylsertraline | 4-(3,4-Dichlor...)
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Affinity Data
Ki: 3nM
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CHEMBL
PC cid
PC sid
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM85219
(CAS_144025-14-9 | Desmethylcitalopram)
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Affinity Data
Ki: 3.60nM
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ChEBI
KEGG
PC cid
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In Depth
Date in BDB:
3/3/2012
Entry Details
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PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
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Affinity Data
Ki: 4.37nM
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Target Info
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ChEBI
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KEGG
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In Depth
Date in BDB:
3/3/2012
Entry Details
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PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM85218
(CAS_39022-39-4 | Oxaprotiline)
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Ki: 4.90nM
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PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
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Copy Entry DOI
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82437
(CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...)
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Affinity Data
Ki: 5.40nM
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Target Info
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ChEBI
PC cid
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82548
(CAS_897-15-4 | NSC_3155 | Dothiepin)
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Affinity Data
Ki: 8.60nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50022784
(Methyl-(3-phenyl-3-o-tolyloxy-propyl)-amine(tomoxe...)
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Affinity Data
Ki: 8.90nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82071
(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
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Affinity Data
Ki: 8.90nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50014247
((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...)
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Affinity Data
Ki: 11nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM35228
(Ludiomil | CHEMBL21731 | Dibencycladine | maprotil...)
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Affinity Data
Ki: 11.1nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50005548
((+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquin...)
Copy SMILES
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Affinity Data
Ki: 15.6nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
PDB
3D Structure (crystal)
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM22870
(CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...)
Copy SMILES
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Affinity Data
Ki: 16nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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PC cid
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Copy SMILES
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Affinity Data
Ki: 17.6nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
Copy SMILES
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Affinity Data
Ki: 18nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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KEGG
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PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50176062
(3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-...)
Copy SMILES
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Affinity Data
Ki: 19.6nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent dopamine transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82217
([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
Copy SMILES
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Affinity Data
Ki: 25nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Affinity Data
Ki: 29.5nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
KEGG
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PC sid
PDB
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
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Affinity Data
Ki: 35nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Copy SMILES
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Affinity Data
Ki: 37nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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PC sid
PDB
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM77970
(CLOMIPRAMINE HYDROCHLORIDE | CHLORIMIPRAMINE | 3-(...)
Copy SMILES
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Affinity Data
Ki: 38nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM22416
(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Copy SMILES
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Affinity Data
Ki: 40nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82548
(CAS_897-15-4 | NSC_3155 | Dothiepin)
Copy SMILES
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Affinity Data
Ki: 46nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Sodium-dependent dopamine transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50005548
((+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquin...)
Copy SMILES
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Affinity Data
Ki: 56nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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PC sid
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Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM22870
(CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...)
Copy SMILES
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Affinity Data
Ki: 58nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
Copy SMILES
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Affinity Data
Ki: 68nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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PC sid
PDB
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82437
(CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...)
Copy SMILES
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Affinity Data
Ki: 70nM
More data for this Ligand-Target Pair
Target Info
PDB
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ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM35256
(MIANSERIN (+) | MIANSERIN | Lerivon | Tolvon | MIA...)
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Ki: 71nM
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Date in BDB:
3/3/2012
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Target
Sodium-dependent dopamine transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50028066
(CHEMBL40733 | Desmethylsertraline | 4-(3,4-Dichlor...)
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Ki: 129nM
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Date in BDB:
3/3/2012
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50240410
(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2...)
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Ki: 149nM
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Date in BDB:
3/3/2012
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50020706
(cis -[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dim...)
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Ki: 152nM
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Date in BDB:
3/3/2012
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50025691
(2-(2-Ethoxy-phenoxymethyl)-morpholine(viloxazine) ...)
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Ki: 155nM
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3/3/2012
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50073444
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
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Ki: 160nM
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Date in BDB:
3/3/2012
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Target
Sodium-dependent serotonin transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50069447
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-e...)
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Ki: 200nM
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Date in BDB:
3/3/2012
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM30130
(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
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Ki: 240nM
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In Depth
Date in BDB:
3/3/2012
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PubMed
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Target
Sodium-dependent dopamine transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50069447
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-e...)
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Affinity Data
Ki: 360nM
More data for this Ligand-Target Pair
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Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50069447
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-e...)
Copy SMILES
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Affinity Data
Ki: 360nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
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PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50028066
(CHEMBL40733 | Desmethylsertraline | 4-(3,4-Dichlor...)
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Ki: 390nM
More data for this Ligand-Target Pair
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
Article
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Target
Sodium-dependent dopamine transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50254790
(NORFLUOXETINE | CHEMBL465123 | (S)-Norfluoxetine)
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Ki: 420nM
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CHEMBL
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In Depth
Date in BDB:
3/3/2012
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PubMed
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Target
Sodium-dependent noradrenaline transporter
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82217
([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
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Ki: 420nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/3/2012
Entry Details
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