Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50007279
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029763(Epiroprim | TCMDC-137295 | 5-(3,5-Diethoxy-4-pyrro...)
Affinity DataIC50: 3nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029763(Epiroprim | TCMDC-137295 | 5-(3,5-Diethoxy-4-pyrro...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027970(Brodimoprim | 5-(4-Bromo-3,5-dimethoxy-benzyl)-pyr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027970(Brodimoprim | 5-(4-Bromo-3,5-dimethoxy-benzyl)-pyr...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027970(Brodimoprim | 5-(4-Bromo-3,5-dimethoxy-benzyl)-pyr...)
Affinity DataIC50: 31nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029763(Epiroprim | TCMDC-137295 | 5-(3,5-Diethoxy-4-pyrro...)
Affinity DataIC50: 42nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataIC50: 390nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060715(6-Bromo-5-[(3,5-dichloro-4-pyrrol-1-yl-phenylamino...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060714(6-Bromo-5-{[(2,5-dimethoxy-phenyl)-methyl-amino]-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060714(6-Bromo-5-{[(2,5-dimethoxy-phenyl)-methyl-amino]-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060715(6-Bromo-5-[(3,5-dichloro-4-pyrrol-1-yl-phenylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060714(6-Bromo-5-{[(2,5-dimethoxy-phenyl)-methyl-amino]-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060717(6-Bromo-5-[(3,4,5-trimethoxy-phenylamino)-methyl]-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060717(6-Bromo-5-[(3,4,5-trimethoxy-phenylamino)-methyl]-...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060715(6-Bromo-5-[(3,5-dichloro-4-pyrrol-1-yl-phenylamino...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060713(6-Bromo-5-{[methyl-(3,4,5-trimethoxy-phenyl)-amino...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060713(6-Bromo-5-{[methyl-(3,4,5-trimethoxy-phenyl)-amino...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060716(6-Bromo-5-[(2,5-dimethoxy-phenylamino)-methyl]-thi...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060717(6-Bromo-5-[(3,4,5-trimethoxy-phenylamino)-methyl]-...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060716(6-Bromo-5-[(2,5-dimethoxy-phenylamino)-methyl]-thi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060716(6-Bromo-5-[(2,5-dimethoxy-phenylamino)-methyl]-thi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060713(6-Bromo-5-{[methyl-(3,4,5-trimethoxy-phenyl)-amino...)
Affinity DataIC50: 1.27E+5nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)