Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50007258
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 2.60nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 0.900nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 53nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.60nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.20nMAssay Description:Compound was evaluated for the stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.90nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 0.600nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Compound was evaluated for the stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.90nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 30.2nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Mouse)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Mouse)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1F(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1F(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
