Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50007112
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058495(3-{2-[2-(Thiophene-2-carbonylsulfanyl)-propionylam...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058491(3-{4-[2-(4-{1-[4-(2-Carboxy-2-methyl-propane-1-sul...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058493((R)-2-{2-[4-(4-Chloro-benzenesulfonylaminocarbonyl...)
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058492((R)-1-{2-[4-(4-Chloro-benzenesulfonylaminocarbonyl...)
Affinity DataIC50: 18nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058474((R)-2-(2-{4-[(6-Hydroxy-3,5,7,8-tetramethyl-chroma...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058486((R)-2-(2-{4-[2-(3,5-Di-tert-butyl-4-hydroxy-phenyl...)
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058480((R)-2-{2-[4-(4-Chloro-benzoylsulfamoyl)-benzoylami...)
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058475((R)-2-(2-{4-[2-(3,5-Di-tert-butyl-4-hydroxy-phenyl...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058485({2-Methyl-1-[(R)-3-(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058489((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 34nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50031201((S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataIC50: 34nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058481((2R,3aR,7aR)-1-(2-{4-[(E)-3-(3,5-Di-tert-butyl-4-e...)
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058487((2R,3aR,7aR)-1-{2-[4-(3,5-Di-tert-butyl-4-hydroxy-...)
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058477((2R,3aR,7aR)-1-(2-{4-[2-(3,5-Di-tert-butyl-4-hydro...)
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058471((2R,3aR,7aR)-1-(2-{4-[(E)-3-(3,5-Di-tert-butyl-4-h...)
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058478((2R,3aR,7aR)-1-[2-(4-{4-[2-(3,5-Di-tert-butyl-4-hy...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058479(2,6-Dimethyl-4-[4-(4-{2-methyl-1-[(R)-3-(3,3,3-tri...)
Affinity DataIC50: 41nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058483((2R,3aR,7aR)-1-(2-{4-[2-(3,5-Di-tert-butyl-4-hydro...)
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058494(3,5-Di-tert-butyl-4-hydroxy-benzoic acid 2,6-di-te...)
Affinity DataIC50: 46nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058490((2R,3aR,7aR)-1-(2-{4-Chloro-3-[2-(3,5-di-tert-buty...)
Affinity DataIC50: 46nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058476((S)-1-[(S)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataIC50: 59nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058482((S)-1-{(R)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058488((S)-1-{(R)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataIC50: 84nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058472((R)-2-(2-Amino-3-methyl-butyryl)-2-aza-bicyclo[2.2...)
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 1.00E+3nMAssay Description:The concentration required to achieve 50% inhibition against pig pancreatic elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 2.00E+3nMAssay Description:The concentration required to achieve 50% inhibition against prolyl endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 1.90E+4nMAssay Description:The concentration required to achieve 50% inhibition against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 2.40E+4nMAssay Description:The concentration required to achieve 50% inhibition against Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 3.80E+4nMAssay Description:The concentration required to achieve 50% inhibition against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 5.80E+4nMAssay Description:The concentration required to achieve 50% inhibition against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed