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Found
65
Enz. Inhib. hit(s) with all data for entry = 5074
Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Affinity Data
Ki: 0.320nM
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Date in BDB:
2/25/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85048
(CHEMBL537481 | Glaxo 1192U90)
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Ki: 4nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85047
(SDZ GLC 756)
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Ki: 7nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005120
(Nemonapride | N-((2S,3S)-1-Benzyl-2-methyl-pyrroli...)
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Ki: 15nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Ki: 15nM
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2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Ki: 15nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005120
(Nemonapride | N-((2S,3S)-1-Benzyl-2-methyl-pyrroli...)
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Ki: 23nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Ki: 26nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
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Ki: 35nM
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 39nM
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50091032
(6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl-a...)
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Ki: 59nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 60nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Mouse)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 65nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81993
(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
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Ki: 68nM
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Date in BDB:
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50020192
(8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...)
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Ki: 68nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85047
(SDZ GLC 756)
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Ki: 75nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81993
(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
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Ki: 110nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Ki: 160nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
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Ki: 192nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81493
(CAS_749-13-3 | TRIFLUORPERIDOL)
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Ki: 200nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 210nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Ki: 220nM
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81444
(NSC_185453 | CAS_185453 | WB 4101 | WB-4101)
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Ki: 237nM
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2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50130290
(Moban | 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,...)
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Ki: 270nM
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Date in BDB:
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50026957
((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...)
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Ki: 300nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 400nM
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 420nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM84342
(EPINEPHRINE | 4-[1-hydroxy-2-(methylamino)ethyl]be...)
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Ki: 427nM
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50007422
((R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4...)
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Ki: 460nM
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Date in BDB:
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21395
(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
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Ki: 775nM
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Date in BDB:
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Ki: 800nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
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Ki: 850nM
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Date in BDB:
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
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Ki: 880nM
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Date in BDB:
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81486
(NSC_4249 | CAS_1050-79-9 | MOPERONE)
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Ki: 880nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Ki: 880nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Ki: 926nM
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Date in BDB:
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM85046
(Aminotetralin-6,7-dihydroxy-(-))
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Ki: 930nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50033112
(Urapidil-5-methyl | CHEMBL420060 | 6-{3-[4-(2-Meth...)
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Ki: 969nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Mouse)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM81775
(Sulpiride-R | Sulpiride-d | Sulpiride-low,(-) | Su...)
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Ki: 1.06E+3nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM21393
(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
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Ki: 1.11E+3nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM50001859
(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
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Ki: 1.21E+3nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(SMR000059324 | Oxymetazoline | cid_66259 | 6-tert-...)
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Ki: 1.26E+3nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001955
(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
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Ki: 1.27E+3nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21393
(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
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Ki: 1.40E+3nM
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Date in BDB:
2/25/2012
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PubMed
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Target
D(2) dopamine receptor
(Mouse)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81774
(Sulpiride-S | CAS_15676-16-1 | Sulpiride-l | SULPI...)
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Ki: 1.47E+3nM
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Date in BDB:
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-2-imidazoline | 2-(2,6-dic...)
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Ki: 1.98E+3nM
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Date in BDB:
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM35234
(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
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Ki: 2.25E+3nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 2.50E+3nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM39344
(PROCAINAMIDE | PROCAINAMIDE HYDROCHLORIDE | 4-azan...)
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Ki: 2.50E+3nM
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Date in BDB:
2/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
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Ki: 3.00E+3nM
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