Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50036553
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 700nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055662((4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055647(10-[2-[1-(Methoxymethyl)-4-[1-(methoxymethyl)-4-[1...)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055646(4-Butyrylamino-1-methoxymethyl-1H-imidazole-2-carb...)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055656(10-[2-[1-(Methoxymethyl)-4-[1-(methoxymethyl)-4-bu...)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055661(4-(4-Dimethylamino-butyrylamino)-1-methoxymethyl-1...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055659(CHEMBL11252 | 2N-[5-(3-amino-3-iminopropylcarbamoy...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055649(10-[[[1-(Methoxymethyl)-2-[[1-(methoxymethyl)-2-[[...)
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055652(10-[[[1-(Methoxymethyl)-2-[[1-(methoxymethyl)-2-ca...)
Affinity DataIC50: 4.29E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055653(10-[[[1-(Methoxymethyl)-2-[[3-(dimethylamino)propy...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055651(10-[2-[1-(Methoxymethyl)-4-[1-(methoxymethyl)-4-[4...)
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055650(10-[[[1-(Methoxymethyl)-2-carbethoxypyrrol-4-yl]ca...)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055663(10-[[[1-(Methoxymethyl)-2-[[1-(methoxymethyl)-2-[[...)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055648(10-[2-[1-(Methoxymethyl)-4-[1-(methoxymethyl)-4-bu...)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055660(CHEMBL307767 | 2N-(3-amino-3-iminopropyl)-4-[4-ami...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed