Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50036469
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18808(2-amino-5-[(3,4-dichlorophenyl)sulfanyl]-6-methyl-...)
Affinity DataIC50: 130nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50: 150nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 340nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)
Affinity DataIC50: 530nMAssay Description:The inhibitory concentration of compound was evaluated on Pneumocystis carini Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)
Affinity DataIC50: 880nMAssay Description:The inhibitory concentration of compound was evaluated on Human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054512(2-Amino-5-(4-chloro-phenylsulfanyl)-6-methyl-3,7-d...)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054508(2-Amino-6-methyl-5-(naphthalen-2-ylsulfanyl)-3,7-d...)
Affinity DataIC50: 2.00E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50: 2.00E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Pneumocystis carini Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18808(2-amino-5-[(3,4-dichlorophenyl)sulfanyl]-6-methyl-...)
Affinity DataIC50: 2.20E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Pneumocystis carini Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.40E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054512(2-Amino-5-(4-chloro-phenylsulfanyl)-6-methyl-3,7-d...)
Affinity DataIC50: 2.60E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054512(2-Amino-5-(4-chloro-phenylsulfanyl)-6-methyl-3,7-d...)
Affinity DataIC50: 3.10E+3nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50: 5.10E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054512(2-Amino-5-(4-chloro-phenylsulfanyl)-6-methyl-3,7-d...)
Affinity DataIC50: 5.30E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Pneumocystis carini Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)
Affinity DataIC50: 5.30E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)
Affinity DataIC50: 8.80E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18795((2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquin...)
Affinity DataIC50: 8.80E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18808(2-amino-5-[(3,4-dichlorophenyl)sulfanyl]-6-methyl-...)
Affinity DataIC50: 1.17E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50: 1.30E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50: 1.50E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Pneumocystis cariniMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50: 1.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18808(2-amino-5-[(3,4-dichlorophenyl)sulfanyl]-6-methyl-...)
Affinity DataIC50: 2.00E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Pneumocystis cariniMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18808(2-amino-5-[(3,4-dichlorophenyl)sulfanyl]-6-methyl-...)
Affinity DataIC50: 2.00E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.00E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.10E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Pneumocystis cariniMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.10E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.40E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.40E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.40E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054512(2-Amino-5-(4-chloro-phenylsulfanyl)-6-methyl-3,7-d...)
Affinity DataIC50: 2.46E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on rat liver (rl)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054508(2-Amino-6-methyl-5-(naphthalen-2-ylsulfanyl)-3,7-d...)
Affinity DataIC50: 2.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054508(2-Amino-6-methyl-5-(naphthalen-2-ylsulfanyl)-3,7-d...)
Affinity DataIC50: 2.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054508(2-Amino-6-methyl-5-(naphthalen-2-ylsulfanyl)-3,7-d...)
Affinity DataIC50: 2.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054512(2-Amino-5-(4-chloro-phenylsulfanyl)-6-methyl-3,7-d...)
Affinity DataIC50: 2.60E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 2.90E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 2.90E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50: 3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50: 3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50: 3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50: 3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054512(2-Amino-5-(4-chloro-phenylsulfanyl)-6-methyl-3,7-d...)
Affinity DataIC50: 3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054512(2-Amino-5-(4-chloro-phenylsulfanyl)-6-methyl-3,7-d...)
Affinity DataIC50: 4.00E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Pneumocystis carini (pc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18808(2-amino-5-[(3,4-dichlorophenyl)sulfanyl]-6-methyl-...)
Affinity DataIC50: 4.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18808(2-amino-5-[(3,4-dichlorophenyl)sulfanyl]-6-methyl-...)
Affinity DataIC50: 4.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18808(2-amino-5-[(3,4-dichlorophenyl)sulfanyl]-6-methyl-...)
Affinity DataIC50: 4.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50: 6.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Pneumocystis carini Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50: 2.44E+5nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50: 7.47E+6nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed