Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50006716
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052668(Adamantane-1-carboxylic acid (S)-1-pyridin-4-yl-et...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052669(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-4-...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052668(Adamantane-1-carboxylic acid (S)-1-pyridin-4-yl-et...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052669(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-4-...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052671(Adamantane-1-carboxylic acid pyridin-4-ylmethyl es...)
Affinity DataIC50: 18nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 26nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052671(Adamantane-1-carboxylic acid pyridin-4-ylmethyl es...)
Affinity DataIC50: 43nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 65nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052672(Adamantane-1-carboxylic acid (R)-1-pyridin-4-yl-et...)
Affinity DataIC50: 74nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052666(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-3-...)
Affinity DataIC50: 92nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052667(Adamantane-1-carboxylic acid (R)-1-pyridin-3-yl-et...)
Affinity DataIC50: 150nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052664(Adamantane-1-carboxylic acid ((S)-1-pyridin-4-yl-e...)
Affinity DataIC50: 210nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052673(Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-et...)
Affinity DataIC50: 230nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052672(Adamantane-1-carboxylic acid (R)-1-pyridin-4-yl-et...)
Affinity DataIC50: 340nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052666(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-3-...)
Affinity DataIC50: 390nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052674(Adamantane-1-carboxylic acid ((R)-1-pyridin-4-yl-e...)
Affinity DataIC50: 430nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052670(Adamantane-1-carboxylic acid pyridin-3-ylmethyl es...)
Affinity DataIC50: 460nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052671(Adamantane-1-carboxylic acid pyridin-4-ylmethyl es...)
Affinity DataIC50: 580nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052667(Adamantane-1-carboxylic acid (R)-1-pyridin-3-yl-et...)
Affinity DataIC50: 580nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052664(Adamantane-1-carboxylic acid ((S)-1-pyridin-4-yl-e...)
Affinity DataIC50: 820nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052673(Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-et...)
Affinity DataIC50: 840nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052675(Adamantane-1-carboxylic acid (pyridin-4-ylmethyl)-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052670(Adamantane-1-carboxylic acid pyridin-3-ylmethyl es...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052675(Adamantane-1-carboxylic acid (pyridin-4-ylmethyl)-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052674(Adamantane-1-carboxylic acid ((R)-1-pyridin-4-yl-e...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052673(Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-et...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052668(Adamantane-1-carboxylic acid (S)-1-pyridin-4-yl-et...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052675(Adamantane-1-carboxylic acid (pyridin-4-ylmethyl)-...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052670(Adamantane-1-carboxylic acid pyridin-3-ylmethyl es...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052672(Adamantane-1-carboxylic acid (R)-1-pyridin-4-yl-et...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052669(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-4-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052667(Adamantane-1-carboxylic acid (R)-1-pyridin-3-yl-et...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052666(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-3-...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed