Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50036429
TargetCysteinyl leukotriene receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052024(montelukast | CHEMBL787)
Affinity DataIC50: 0.5nMAssay Description:Compound were tested for inhibitory activity against Cysteinyl leukotriene D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037390(3-{(S)-2-(2-Carboxy-ethyl)-7-[3-(2-cyclopropylmeth...)
Affinity DataIC50: 1.30nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052017(SC-51146 | 3-{7-[3-(2-Cyclopropylmethyl-3-methoxy-...)
Affinity DataIC50: 1.5nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052029(Sodium; 3-[(R)-{3-[(E)-2-(7-chloro-quinolin-2-yl)-...)
Affinity DataIC50: 3.10nMAssay Description:Compound were tested for inhibitory activity against Cysteinyl leukotriene D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052021(4-[5-(4-Carbamimidoyl-phenoxy)-pentyloxy]-N,N-diis...)
Affinity DataIC50: 4nMAssay Description:Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029482(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataIC50: 4nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 8.40nMAssay Description:Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001611((Z)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50: 13nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001610(CHEMBL14823 | CGS 24115 | 7-[3-(4-Acetyl-3-methoxy...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory activity against LTB4 (leukotriene) bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 23nMAssay Description:Binding affinity of compound for 5-lipoxygenase activating protein protein by FLAP binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCysteinyl leukotriene receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006798(2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...)
Affinity DataIC50: 23nMAssay Description:Compound was tested for inhibitory activity against LTD4 (leukotriene).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052028(LY-247826 | 7-[3-(4-Acetyl-2-ethyl-5-hydroxy-pheno...)
Affinity DataIC50: 40nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataIC50: 87nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataIC50: 4.00E+3nMAssay Description:Compound was tested for binding affinity against Cysteinyl leukotriene D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50009071(Ro-23-3544 | 6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-p...)
Affinity DataIC50: 4.00E+3nMAssay Description:Compound was tested for inhibitory activity against LTD4 (leukotriene).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029464(LY-292728 | 5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-f...)
Affinity DataKi:  0.470nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052027(Ticolubant | (E)-3-[6-(2,6-Dichloro-phenylsulfanyl...)
Affinity DataKi:  0.800nMAssay Description:Compound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052025(6-{2-(2-Carboxy-ethyl)-3-[6-(4-oxo-8-propyl-chroma...)
Affinity DataKi:  1nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037382(ONO 4057 | 5-{2-(2-Carboxy-ethyl)-3-[6-(4-methoxy-...)
Affinity DataKi:  3.70nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037385(3-{6-((E)-2-Carboxy-vinyl)-5-[6-(4-methoxy-phenyl)...)
Affinity DataKi:  7.10nMAssay Description:Compound was tested for binding affinity against Leukotriene B4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029450(LY-193111 | 2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-b...)
Affinity DataKi:  25nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed