Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50006515
TargetSterol O-acyltransferase 1(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050356(2,2-Dimethyl-dodecanoic acid (5-dimethylamino-2,2,...)
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050362(2,2-Dimethyl-dodecanoic acid (7-methoxy-4-oxo-chro...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050362(2,2-Dimethyl-dodecanoic acid (7-methoxy-4-oxo-chro...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050356(2,2-Dimethyl-dodecanoic acid (5-dimethylamino-2,2,...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050367(Hexadecanoic acid (2,2,6-trimethyl-2,3-dihydro-ben...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050381(Hexadecanoic acid (2,2,4,6-tetramethyl-2,3-dihydro...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050364(4-Decyloxy-N-(2,2,4,6-tetramethyl-2,3-dihydro-benz...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050372(2,2-Dimethyl-tetradecanoic acid (2,2,4,6-tetrameth...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050352(2,2-Dimethyl-dodecanoic acid (2,2,4,6-tetramethyl-...)
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050365(5-(4-Isobutyl-phenyl)-2,2-dimethyl-pentanoic acid ...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050380(2,2-Dimethyl-dodecanoic acid (2,2,4,6-tetramethyl-...)
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050366(2,2-Dimethyl-8-p-tolyloxy-octanoic acid (2,2,4,6-t...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050376(8-Isobutoxy-2,2-dimethyl-octanoic acid (2,2,4,6-te...)
Affinity DataIC50: 59nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050375(2,2-Dimethyl-dodecanoic acid (5-amino-2,2,4,6-tetr...)
Affinity DataIC50: 59nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050363(8-(4-Chloro-phenoxy)-2,2-dimethyl-octanoic acid (2...)
Affinity DataIC50: 76nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050374(2,2-Dimethyl-8-phenyl-octanoic acid (2,2,4,6-tetra...)
Affinity DataIC50: 81nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050371(2,2-Dimethyl-7-phenoxy-heptanoic acid (2,2,4,6-tet...)
Affinity DataIC50: 86nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050355(4-Dodecyloxy-N-(2,2,4,6-tetramethyl-2,3-dihydro-be...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050359(2,2-Dimethyl-7-phenyl-heptanoic acid (2,2,4,6-tetr...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050379(2,2-Dimethyl-decanoic acid (2,2,4,6-tetramethyl-2,...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 149nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050361(7-(4-Chloro-phenoxy)-2,2-dimethyl-heptanoic acid (...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050358(1-Decyl-cyclopentanecarboxylic acid (2,2,4,6-tetra...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050350(4-Octyloxy-N-(2,2,4,6-tetramethyl-2,3-dihydro-benz...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050353(4-[6-(4-Chloro-phenoxy)-hexyloxy]-N-(2,2,4,6-tetra...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050369(4-(6-Propoxy-hexyloxy)-N-(2,2,4,6-tetramethyl-2,3-...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050377(2,2-Dimethyl-6-phenyl-hexanoic acid (2,2,4,6-tetra...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050357(1-Decyl-cyclopentanecarboxylic acid (2,2,6-trimeth...)
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050373(5-(4-Chloro-phenoxy)-2,2-dimethyl-pentanoic acid (...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050368(1-Decyl-cyclopentanecarboxylic acid (5-chloro-2,2,...)
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050360(6-(4-Chloro-phenoxy)-2,2-dimethyl-hexanoic acid (2...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050370(6-Benzyloxy-2,2-dimethyl-hexanoic acid (2,2,4,6-te...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050354(2,2-Dimethyl-8-piperidin-1-yl-octanoic acid (2,2,4...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050378(1-Decyl-cyclopentanecarboxylic acid (2,2-dimethyl-...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50050351(Hexadecanoic acid (2,2-dimethyl-2,3-dihydro-benzof...)
Affinity DataIC50: 890nMAssay Description:Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed