Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50006142
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001611((Z)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of binding of [3H]LTB4 to receptor on nonradioactive LTB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045092(LY-210073 | 5-(2-Carboxy-ethyl)-6-[(E)-6-(4-methox...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001611((Z)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50: 13nMAssay Description:Inhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045091(5-(2-Carboxy-ethyl)-6-decyloxy-9-oxo-9H-xanthene-2...)
Affinity DataIC50: 43nMAssay Description:Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045092(LY-210073 | 5-(2-Carboxy-ethyl)-6-[(E)-6-(4-methox...)
Affinity DataIC50: 133nMAssay Description:The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045096(3-[3-(2-Carboxy-ethyl)-4-decyloxy-benzoyl]-benzoic...)
Affinity DataIC50: 210nMAssay Description:Inhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045091(5-(2-Carboxy-ethyl)-6-decyloxy-9-oxo-9H-xanthene-2...)
Affinity DataIC50: 513nMAssay Description:The antagonist activity measured as inhibition of LTB4 response in aggregation of neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045093(7-(2-Carboxy-ethyl)-6-decyloxy-9-oxo-9H-xanthene-2...)
Affinity DataIC50: 832nMAssay Description:Inhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045094(7-(2-Carboxy-ethyl)-6-decyloxy-9-oxo-9H-xanthene-4...)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045095(5-(2-Carboxy-ethyl)-6-decyloxy-9-oxo-9H-xanthene-4...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of specific binding of [3H]LTB4 ( 0.1 nM) to LTB4 receptor on intact human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045092(LY-210073 | 5-(2-Carboxy-ethyl)-6-[(E)-6-(4-methox...)
Affinity DataKi:  5.90nMAssay Description:Inhibition constant against binding of [3H]LTB4 to human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed