Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50006085
TargetSigma non-opioid intracellular receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi:  4.82E+3nMAssay Description:Tested for in vitro inhibition of the displacement of (+)-[3H]pentazocine from sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi:  6.95E+3nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]mazindol from GABA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((5S,10S)-(+)-5-methyl-10,11-dihydro-5Hdibenzo[a,d]...)
Affinity DataKi:  4.09E+4nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]mazindol from GABA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((5S,10S)-(+)-5-methyl-10,11-dihydro-5Hdibenzo[a,d]...)
Affinity DataKi:  5.92E+4nMAssay Description:Tested for in vitro inhibition of the displacement of (+)-[3H]pentazocine from sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]FOXY from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((5S,10S)-(+)-5-methyl-10,11-dihydro-5Hdibenzo[a,d]...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]FOXY from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50044427(1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexade...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]quinuclidinyl benzilate muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((5S,10S)-(+)-5-methyl-10,11-dihydro-5Hdibenzo[a,d]...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]QNB from CNS receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed