Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50006026
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50008735(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM21393(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
Affinity DataIC50: 1.10nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043891(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 1.40nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043882(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 2nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043892(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 8.80nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 12.8nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043884(1-[3-(3,4-Dihydro-naphthalen-1-yl)-propyl]-4-(2-me...)
Affinity DataIC50: 14.7nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043884(1-[3-(3,4-Dihydro-naphthalen-1-yl)-propyl]-4-(2-me...)
Affinity DataIC50: 15.7nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043892(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 17.4nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043893(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 18.3nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043886(1-(3-Chloro-phenyl)-4-[3-(8-methoxy-3,4-dihydro-na...)
Affinity DataIC50: 31.4nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043888(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 55.9nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043881(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 63.6nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043882(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 90.6nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043891(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 119nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043885(1-(3-Chloro-phenyl)-4-[3-(6-methoxy-3,4-dihydro-na...)
Affinity DataIC50: 131nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043889(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 138nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043887(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 147nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043883(1-(2,5-Dimethoxy-phenyl)-4-[3-(6-methoxy-3,4-dihyd...)
Affinity DataIC50: 161nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043883(1-(2,5-Dimethoxy-phenyl)-4-[3-(6-methoxy-3,4-dihyd...)
Affinity DataIC50: 201nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 222nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043893(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 303nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043886(1-(3-Chloro-phenyl)-4-[3-(8-methoxy-3,4-dihydro-na...)
Affinity DataIC50: 484nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043888(1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 644nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043885(1-(3-Chloro-phenyl)-4-[3-(6-methoxy-3,4-dihydro-na...)
Affinity DataIC50: 768nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043887(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 777nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043881(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 778nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043889(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043890(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding of radioligand [3H]spiroperidol to dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50043890(1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro ability to inhibit binding of radioligand [3H]8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed