Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50036187
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078452((S)-3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039549(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042799(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 13nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042804(2-Amino-7-(3-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042803(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042807(2-Amino-7-[1-(3-chloro-phenyl)-3-hydroxy-propyl]-3...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078452((S)-3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]...)
Affinity DataIC50: 31nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042363({2-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)...)
Affinity DataIC50: 35nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50: 47nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039547(2-amino-7-benzyl-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-...)
Affinity DataIC50: 51nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042809(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 85nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042808(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 97nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042804(2-Amino-7-(3-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078450((R)-3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]...)
Affinity DataIC50: 160nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042799(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 187nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042801(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039547(2-amino-7-benzyl-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Mouse)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042363({2-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)...)
Affinity DataIC50: 450nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042805({3-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)...)
Affinity DataIC50: 620nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078450((R)-3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]...)
Affinity DataIC50: 900nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042808(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042361({3-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042807(2-Amino-7-[1-(3-chloro-phenyl)-3-hydroxy-propyl]-3...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039549(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042803(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Mouse)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042802(2-Amino-7-(1-cyclohexyl-3-hydroxy-propyl)-3,5-dihy...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4 determined by measuring 3H release from [3H]-inosineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042801(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042805({3-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042361({3-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042809(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Mouse)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042802(2-Amino-7-(1-cyclohexyl-3-hydroxy-propyl)-3,5-dihy...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4 determined by measuring 3H release from [3H]-inosineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Mouse)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039549(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)
Affinity DataKi:  5nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4 determined by measuring 3H release from [3H]-inosineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033666({[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity against purine binding site of Purine nucleoside PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033666({[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity against hydrophobic pocket of Purine nucleoside PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033666({[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity against phosphate binding site of Purine nucleoside PhosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed