Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50036219
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50005534(CHEMBL279556 | 1-(1-(benzo[b]thiophen-2-yl)cyclohe...)
Affinity DataIC50: 0.660nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040193(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-pyrrolidine...)
Affinity DataIC50: 6.70nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040193(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-pyrrolidine...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040191(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-pyrrolidin...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040199(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-piperidine...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040189(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-piperidine...)
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040191(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-pyrrolidin...)
Affinity DataIC50: 26nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040192(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-azepane | C...)
Affinity DataIC50: 36nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040192(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-azepane | C...)
Affinity DataIC50: 36nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50005534(CHEMBL279556 | 1-(1-(benzo[b]thiophen-2-yl)cyclohe...)
Affinity DataIC50: 41nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040197(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-pyrrolidin...)
Affinity DataIC50: 52nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040197(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-pyrrolidin...)
Affinity DataIC50: 52nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040198(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane | ...)
Affinity DataIC50: 62nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040198(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane | ...)
Affinity DataIC50: 62nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040196(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-azepane | ...)
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040199(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-piperidine...)
Affinity DataIC50: 76nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 107nMAssay Description:Binding affinity of compound at site labeled by [3H]-cocaine in rat forebrain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040189(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-piperidine...)
Affinity DataIC50: 111nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040190(1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...)
Affinity DataIC50: 123nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 187nMAssay Description:Binding affinity for compound at site labeled by [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) in rat forebrain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040196(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-azepane | ...)
Affinity DataIC50: 386nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040194(1-Benzo[b]thiophen-2-yl-cycloheptylamine | CHEMBL1...)
Affinity DataIC50: 416nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040195(1-Benzo[b]thiophen-2-yl-cyclopentylamine | CHEMBL1...)
Affinity DataIC50: 630nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040190(1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...)
Affinity DataIC50: 684nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040195(1-Benzo[b]thiophen-2-yl-cyclopentylamine | CHEMBL1...)
Affinity DataIC50: 933nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040194(1-Benzo[b]thiophen-2-yl-cycloheptylamine | CHEMBL1...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50001028(Talwin | PENTAZOCINE (+) | Pentazocine,(+/-) | 6,1...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040191(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-pyrrolidin...)
Affinity DataKi:  125nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040193(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-pyrrolidine...)
Affinity DataKi:  168nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040192(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-azepane | C...)
Affinity DataKi:  674nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040197(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-pyrrolidin...)
Affinity DataKi:  720nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040199(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-piperidine...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040195(1-Benzo[b]thiophen-2-yl-cyclopentylamine | CHEMBL1...)
Affinity DataKi:  1.73E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM83449(cid_9795678 | PHENCYCLIDINE | SMR001338811 | Phenc...)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040189(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-piperidine...)
Affinity DataKi:  2.23E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040196(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-azepane | ...)
Affinity DataKi:  2.71E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040198(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane | ...)
Affinity DataKi:  2.89E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040190(1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...)
Affinity DataKi:  3.17E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040194(1-Benzo[b]thiophen-2-yl-cycloheptylamine | CHEMBL1...)
Affinity DataKi:  9.17E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed