Compile Data Set for Download or QSAR
Report error Found 118 Enz. Inhib. hit(s) with all data for entry = 50005678
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028600(1-(8-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataKi:  0.540nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028602(1-(2-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataKi:  0.900nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi:  1nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi:  1nMAssay Description:Affinity was evaluated by inhibition of [3H]spiperone binding to COS cells transfected with human dopamine D-2(long) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028598(1-Dibenzo[b,f]oxepin-10-yl-4-methyl-piperazine | C...)
Affinity DataKi:  2nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi:  2nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028600(1-(8-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataKi:  2.5nMAssay Description:Affinity was evaluated by inhibition of [3H]spiperone binding to COS cells transfected with human dopamine D-2(long) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028600(1-(8-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataKi:  3nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028599(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi:  3nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028976(4-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-me...)
Affinity DataKi:  3nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028976(4-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-me...)
Affinity DataKi:  3nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028602(1-(2-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataKi:  3nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028600(1-(8-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataKi:  3nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028598(1-Dibenzo[b,f]oxepin-10-yl-4-methyl-piperazine | C...)
Affinity DataKi:  4nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010598(CHEMBL91310 | 1-Methyl-4-(5-methylene-5H-dibenzo[a...)
Affinity DataKi:  4.70nMAssay Description:Affinity was evaluated as inhibition constant for dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM22871(13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azat...)
Affinity DataKi:  4.90nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi:  6nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028598(1-Dibenzo[b,f]oxepin-10-yl-4-methyl-piperazine | C...)
Affinity DataKi:  6nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028602(1-(2-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataKi:  6nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028599(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi:  7nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010594(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
Affinity DataKi:  7nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  8nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  8nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028602(1-(2-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataKi:  8.70nMAssay Description:Affinity was evaluated by inhibition of [3H]spiperone binding to COS cells transfected with human dopamine D-2(long) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010598(CHEMBL91310 | 1-Methyl-4-(5-methylene-5H-dibenzo[a...)
Affinity DataKi:  11nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010594(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
Affinity DataKi:  11nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028980(CHEMBL7828 | Isoloxapine | 8-chloro-11-(4-methylpi...)
Affinity DataKi:  11nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50036438(1-Methyl-4-(5-methyl-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  12nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010594(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
Affinity DataKi:  14nMAssay Description:Affinity was evaluated as inhibition constant for dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50036438(1-Methyl-4-(5-methyl-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  16nMAssay Description:Affinity was evaluated as inhibition constant for dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010594(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
Affinity DataKi:  16nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010598(CHEMBL91310 | 1-Methyl-4-(5-methylene-5H-dibenzo[a...)
Affinity DataKi:  18nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028980(CHEMBL7828 | Isoloxapine | 8-chloro-11-(4-methylpi...)
Affinity DataKi:  19nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM22871(13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azat...)
Affinity DataKi:  21nMAssay Description:Affinity was evaluated by inhibition of [3H]spiperone binding to COS cells transfected with human dopamine D-2(long) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  21nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028598(1-Dibenzo[b,f]oxepin-10-yl-4-methyl-piperazine | C...)
Affinity DataKi:  21nMAssay Description:Affinity was evaluated by inhibition of [3H]spiperone binding to COS cells transfected with human dopamine D-2(long) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010594(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
Affinity DataKi:  22nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028980(CHEMBL7828 | Isoloxapine | 8-chloro-11-(4-methylpi...)
Affinity DataKi:  23nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50039671(1-Methyl-4-(5-methylene-5H-dibenzo[a,d]cyclohepten...)
Affinity DataKi:  30nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010598(CHEMBL91310 | 1-Methyl-4-(5-methylene-5H-dibenzo[a...)
Affinity DataKi:  31nMAssay Description:Affinity was evaluated by inhibition of [3H]GR-65630 binding to NG108-15 cell transfected with cloned rat 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50039669(1-[5-Eth-(Z)-ylidene-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  35nMAssay Description:Affinity was evaluated by inhibition of [3H]GR-65630 binding to NG108-15 cell transfected with cloned rat 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50039671(1-Methyl-4-(5-methylene-5H-dibenzo[a,d]cyclohepten...)
Affinity DataKi:  35nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50036438(1-Methyl-4-(5-methyl-5H-dibenzo[a,d]cyclohepten-10...)
Affinity DataKi:  36nMAssay Description:Affinity was evaluated by inhibition of [125I]LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010591(CHEMBL73538 | 11-(4-Methyl-piperazin-1-yl)-5H-dibe...)
Affinity DataKi:  39nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028980(CHEMBL7828 | Isoloxapine | 8-chloro-11-(4-methylpi...)
Affinity DataKi:  39nMAssay Description:Affinity was evaluated by inhibition of [3H]GR-65630 binding to NG108-15 cell transfected with cloned rat 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50010591(CHEMBL73538 | 11-(4-Methyl-piperazin-1-yl)-5H-dibe...)
Affinity DataKi:  40nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataKi:  40nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028976(4-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-me...)
Affinity DataKi:  41nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028598(1-Dibenzo[b,f]oxepin-10-yl-4-methyl-piperazine | C...)
Affinity DataKi:  41nMAssay Description:Affinity was evaluated by inhibition of [3H]GR-65630 binding to NG108-15 cell transfected with cloned rat 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  43nMAssay Description:Affinity was evaluated as inhibition constant for dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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