Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50005666
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039566((3-Nitro-pyridin-2-yl)-(3-(R)-1-pyrrolidin-2-ylmet...)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039564([3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol-5...)
Affinity DataEC50:  47nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataEC50:  97nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039565([3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-(3-nitro...)
Affinity DataEC50:  170nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039564([3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol-5...)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039567([3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-5-yl]-(3-ni...)
Affinity DataEC50:  885nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039565([3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-(3-nitro...)
Affinity DataEC50:  2nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  10nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039567([3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-5-yl]-(3-ni...)
Affinity DataEC50:  2nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  5.20nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039566((3-Nitro-pyridin-2-yl)-(3-(R)-1-pyrrolidin-2-ylmet...)
Affinity DataEC50:  220nMAssay Description:Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 3nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039564([3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol-5...)
Affinity DataIC50: 3.10nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 5.20nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039566((3-Nitro-pyridin-2-yl)-(3-(R)-1-pyrrolidin-2-ylmet...)
Affinity DataIC50: 6.20nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039565([3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-(3-nitro...)
Affinity DataIC50: 10nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039567([3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-5-yl]-(3-ni...)
Affinity DataIC50: 15nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039564([3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol-5...)
Affinity DataIC50: 33nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 61nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039565([3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-(3-nitro...)
Affinity DataIC50: 73nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039566((3-Nitro-pyridin-2-yl)-(3-(R)-1-pyrrolidin-2-ylmet...)
Affinity DataIC50: 120nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50039567([3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-5-yl]-(3-ni...)
Affinity DataIC50: 320nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 640nMAssay Description:Binding affinity was measured against serotonin 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed