Compile Data Set for Download or QSAR
Report error Found 126 Enz. Inhib. hit(s) with all data for entry = 50036260
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039315((1S,9aR,11aS)-5,9a,11a-Trimethyl-1-(3-methyl-butyr...)
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039259((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.120nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039294((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.160nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50043604(17-tert-Butylcarbamoyl-10,13-dimethyl-2,7,8,9,10,1...)
Affinity DataIC50: 0.180nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 0.180nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039288((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039295(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.230nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039320((4aR,6aS,7S)-1,4a,6a-Trimethyl-2-oxo-hexadecahydro...)
Affinity DataIC50: 0.230nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039278((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039318((1S,9aR,11aS)-1-Butyryl-9a,11a-dimethyl-1,2,3,3a,3...)
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039302(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039312((1S,9aR,11aS)-5,6,9a,11a-Tetramethyl-7-oxo-2,3,3a,...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039273((1S,9aR,11aS)-6-Bromo-9a,11a-dimethyl-1-(3-methyl-...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039296((1S,9aR,11aS)-9a,11a-Dimethyl-1-(piperidine-1-carb...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039282((1S,9aR,11aS)-9a,11a-Dimethyl-1-(2,4,6-triisopropy...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039275((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.600nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039285((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.880nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039284(9a,11a-Dimethyl-1-(thiomorpholine-4-carbonyl)-1,2,...)
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039305((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-5-propyl-2,3,3...)
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039304((1S,9aR,11aS)-6,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039308((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 1.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039256((1S,9aR,11aS)-6-Bromo-5,9a,11a-trimethyl-7-oxo-2,3...)
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039261((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039283((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039263((10S,13S,17S)-10,13-Dimethyl-3-oxo-1,2,3,6,7,8,9,1...)
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039291((1S,9aR,11aS)-6-Chloro-9a,11a-dimethyl-7-oxo-2,3,3...)
Affinity DataIC50: 1.90nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039306((1S,9aR,11aS)-6-Bromo-9a,11a-dimethyl-7-oxo-2,3,3a...)
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039271((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 2.30nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039287((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 2.40nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039266((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039270((1S,9aR,11aS)-8,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 3.40nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039264((1S,9aR,11aS)-5-Ethyl-9a,11a-dimethyl-7-oxo-2,3,3a...)
Affinity DataIC50: 3.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039322((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 3.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039267((1S,10aR,12aS)-10a,12a-Dimethyl-8-oxo-1,2,3,3a,3b,...)
Affinity DataIC50: 3.80nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039323((1S,9aR,11aS)-6,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 3.90nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039279((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-5-propyl-2,3,3...)
Affinity DataIC50: 4.20nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039269((10S,13S,17S)-10,13-Dimethyl-3-oxo-1,2,3,6,7,8,9,1...)
Affinity DataIC50: 4.40nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039319((1S,9aR,11aS)-5,6,9a,11a-Tetramethyl-7-oxo-2,3,3a,...)
Affinity DataIC50: 4.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039310((1S,9aR,11aS)-5-Isopropyl-9a,11a-dimethyl-7-oxo-2,...)
Affinity DataIC50: 4.90nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039307((10S,13S,17S)-6,10,13-Trimethyl-3-oxo-1,2,3,6,7,8,...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039258((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 5.70nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039292((1S,9aR,11aS)-6-Iodo-9a,11a-dimethyl-7-oxo-2,3,3a,...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039309((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 6.70nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039293(9a,11a-Dimethyl-1-(morpholine-4-carbonyl)-1,2,3,3a...)
Affinity DataIC50: 7.10nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039297((1S,9aR,11aS)-6,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 8.10nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039289((1S,9aR,11aS)-5,6,9a,11a-Tetramethyl-7-oxo-2,3,3a,...)
Affinity DataIC50: 8.60nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039290((1S,9aR,11aS)-5-Hexyl-9a,11a-dimethyl-7-oxo-2,3,3a...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039300((1S,9aR,11aS)-5-Butyl-9a,11a-dimethyl-7-oxo-2,3,3a...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039260(9a,11a-Dimethyl-1-(piperazine-1-carbonyl)-1,2,3,3a...)
Affinity DataIC50: 33nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039262((1S,9aR,11aS)-5-Benzyl-9a,11a-dimethyl-7-oxo-2,3,3...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 126 total ) | Next | Last >>
Jump to: