Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50036253
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039111(S-(N-Hydroxy-N-(4-bromophenyl)carbamoyl)glutathion...)
Affinity DataKi:  14nMAssay Description:Tested for inhibitory activity against human erythrocyte glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039108(S-(N-Hydroxy-N-(4-chlorophenyl)carbamoyl)glutathio...)
Affinity DataKi:  46nMAssay Description:Tested for inhibitory activity against human erythrocyte glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039113(S-(N-Hydroxy-N-phenylcarbamoyl)glutathione)
Affinity DataKi:  160nMAssay Description:Tested for inhibitory activity against human erythrocyte glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039111(S-(N-Hydroxy-N-(4-bromophenyl)carbamoyl)glutathion...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of the hydrolysis of S-D-lactoylglutathione...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039111(S-(N-Hydroxy-N-(4-bromophenyl)carbamoyl)glutathion...)
Affinity DataKi:  1.20E+3nMAssay Description:Tested for inhibitory activity against yeast glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039110(S-(N-Methyl-N-hydroxycarbomyl)ethylglutathione)
Affinity DataKi:  1.70E+3nMAssay Description:Tested for inhibitory activity against human erythrocyte glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039108(S-(N-Hydroxy-N-(4-chlorophenyl)carbamoyl)glutathio...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of the hydrolysis of S-D-lactoylglutathione...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039108(S-(N-Hydroxy-N-(4-chlorophenyl)carbamoyl)glutathio...)
Affinity DataKi:  3.60E+3nMAssay Description:Tested for inhibitory activity against yeast glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039113(S-(N-Hydroxy-N-phenylcarbamoyl)glutathione)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition constant for the inhibition of the hydrolysis of S-D-lactoylglutathione by glyoxalase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039113(S-(N-Hydroxy-N-phenylcarbamoyl)glutathione)
Affinity DataKi:  1.10E+4nMAssay Description:Tested for inhibitory activity against yeast glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039110(S-(N-Methyl-N-hydroxycarbomyl)ethylglutathione)
Affinity DataKi:  6.80E+4nMAssay Description:Tested for inhibitory activity against yeast glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039110(S-(N-Methyl-N-hydroxycarbomyl)ethylglutathione)
Affinity DataKi:  4.26E+5nMAssay Description:Inhibition constants obtained from using the enediol analogs as competitive inhibitors for the inhibition of the hydrolysis of S-D-lactoylglutathione...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039115(S-(N-Methyl-N-hydroxycarbomyl)glutathione | CHEMBL...)
Affinity DataKi:  6.80E+5nMAssay Description:Tested for inhibitory activity against yeast glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039114(1,2-Dicarboxy-3-propionylsulfanyl-propyl-ammonium)
Affinity DataKi:  1.98E+6nMAssay Description:Tested for inhibitory activity against yeast glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039109(S-D-Lactoylglutathione)
Affinity DataKi:  2.23E+6nMAssay Description:Tested for inhibitory activity against yeast glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039116(S-D-Lactoylethylglutathione | CHEMBL68031)
Affinity DataKi:  3.16E+6nMAssay Description:Tested for inhibitory activity against yeast glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50039112(S-(N-Methyl-N-carbomyl)glutathione)
Affinity DataKi:  5.67E+6nMAssay Description:Tested for inhibitory activity against yeast glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed