Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50005625
LigandPNGBDBM50038991(Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4...)
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038975(Benzo[1,3]dioxol-5-ylmethyl-(6-methylsulfanyl-quin...)
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038992(4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038973(Benzo[1,3]dioxol-5-ylmethyl-(6-methyl-quinazolin-4...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038982(Benzo[1,3]dioxol-5-ylmethyl-(6-methoxy-quinazolin-...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038979(Benzo[1,3]dioxol-5-ylmethyl-(7-methoxy-6-methylsul...)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038978(Benzo[1,3]dioxol-5-ylmethyl-(6,7,8-trimethoxy-quin...)
Affinity DataIC50: 360nMAssay Description:Inhibition of cGMP-inhibited PDE 3 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038995(Benzo[1,3]dioxol-5-ylmethyl-(6-ethoxy-quinazolin-4...)
Affinity DataIC50: 380nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038988(Benzo[1,3]dioxol-5-ylmethyl-(6-methanesulfinyl-qui...)
Affinity DataIC50: 380nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038986(3-Benzo[1,3]dioxol-5-ylmethyl-6,7,8-trimethoxy-3H-...)
Affinity DataIC50: 530nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038998(4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...)
Affinity DataIC50: 620nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 720nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50039001(Benzo[1,3]dioxol-5-ylmethyl-(5,6-dimethoxy-quinazo...)
Affinity DataIC50: 730nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM15296(Milrinone | CHEMBL189 | 6-methyl-2-oxo-5-pyridin-4...)
Affinity DataIC50: 740nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038976(4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...)
Affinity DataIC50: 770nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038999(Benzo[1,3]dioxol-5-ylmethyl-(6-methanesulfonyl-qui...)
Affinity DataIC50: 810nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038989(Benzo[1,3]dioxol-5-ylmethyl-(6,8-dimethoxy-quinazo...)
Affinity DataIC50: 810nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038977(Benzo[1,3]dioxol-5-ylmethyl-(6,7-dimethoxy-quinazo...)
Affinity DataIC50: 840nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038974({4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazoli...)
Affinity DataIC50: 930nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038996(4-(Benzo[1,3]dioxol-5-ylmethoxy)-6,7,8-trimethoxy-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038981(Benzo[1,3]dioxol-5-ylmethyl-(7-chloro-quinazolin-4...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038987(4-(Benzo[1,3]dioxol-5-ylmethoxy)-6-methylsulfanyl-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038980(Benzo[1,3]dioxol-5-ylmethyl-[1,3]dioxolo[4,5-g]qui...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038985(3-Benzo[1,3]dioxol-5-ylmethyl-6-methylsulfanyl-3H-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038994(4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50039000({4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazoli...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038993(3-Benzo[1,3]dioxol-5-ylmethyl-7-methoxy-6-methylsu...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038983(Benzo[1,3]dioxol-5-ylmethyl-quinazolin-4-yl-amine ...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038990(Benzo[1,3]dioxol-5-ylmethyl-(8-methoxy-quinazolin-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038984(4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038997(3-Benzo[1,3]dioxol-5-ylmethyl-7-chloro-3H-quinazol...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibitory activity against cGMP-phosphodiesterase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038978(Benzo[1,3]dioxol-5-ylmethyl-(6,7,8-trimethoxy-quin...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of cGMP stimulated-PDE 2 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038973(Benzo[1,3]dioxol-5-ylmethyl-(6-methyl-quinazolin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP stimulated-PDE 2 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038992(4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP-inhibited PDE 3 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038975(Benzo[1,3]dioxol-5-ylmethyl-(6-methylsulfanyl-quin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cAMP specific-PDE 4 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038991(Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP-inhibited PDE 3 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038991(Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cAMP specific-PDE 4 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038992(4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP stimulated-PDE 2 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038973(Benzo[1,3]dioxol-5-ylmethyl-(6-methyl-quinazolin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP-inhibited PDE 3 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038982(Benzo[1,3]dioxol-5-ylmethyl-(6-methoxy-quinazolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP stimulated-PDE 2 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038982(Benzo[1,3]dioxol-5-ylmethyl-(6-methoxy-quinazolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cAMP specific-PDE 4 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038991(Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP stimulated-PDE 2 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038978(Benzo[1,3]dioxol-5-ylmethyl-(6,7,8-trimethoxy-quin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP-inhibited PDE 3 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038975(Benzo[1,3]dioxol-5-ylmethyl-(6-methylsulfanyl-quin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP-inhibited PDE 3 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038992(4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cAMP specific-PDE 4 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038982(Benzo[1,3]dioxol-5-ylmethyl-(6-methoxy-quinazolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cAMP specific-PDE 4 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50038975(Benzo[1,3]dioxol-5-ylmethyl-(6-methylsulfanyl-quin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP stimulated-PDE 2 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038978(Benzo[1,3]dioxol-5-ylmethyl-(6,7,8-trimethoxy-quin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cAMP specific-PDE 4 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50038973(Benzo[1,3]dioxol-5-ylmethyl-(6-methyl-quinazolin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cAMP specific-PDE 4 from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed