Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 50036293
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037991({[3-[(1-Carbamimidoyl-piperidin-3-ylmethyl)-carbam...)
Affinity DataKi:  0.270nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037976({Benzyl-[(S)-3-[((S)-1-carbamimidoyl-piperidin-3-y...)
Affinity DataKi:  0.680nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037995({[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataKi:  0.710nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037984({Butyl-[(S)-3-[((S)-1-carbamimidoyl-piperidin-3-yl...)
Affinity DataKi:  0.860nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037983((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037997((S)-4-Azocan-1-yl-N-(1-carbamimidoyl-piperidin-3-y...)
Affinity DataKi:  4.80nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037994((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  6.70nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037992((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-3...)
Affinity DataKi:  9nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037974((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037978({[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037987((R)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-3-(1H...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037993((S)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-4-mor...)
Affinity DataKi:  19nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038001(CHEMBL1166 | (2R,4S)-1-[5-Guanidino-2-(3-methyl-1,...)
Affinity DataKi:  20nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037974((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL537204 | CHEMBL20...)
Affinity DataKi:  31nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  32nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037982((R)-3-(4-Acetylamino-phenyl)-N-(1-carbamimidoyl-pi...)
Affinity DataKi:  38nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  47nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037977((R)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-(na...)
Affinity DataKi:  63nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037979({Benzyl-[(S)-3-[((S)-1-carbamimidoyl-piperidin-3-y...)
Affinity DataKi:  70nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037998({[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataKi:  86nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037980(1-[(S)-3-[(1-Carbamimidoyl-piperidin-3-ylmethyl)-c...)
Affinity DataKi:  93nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037972({[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataKi:  100nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037985({[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataKi:  110nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038000((R)-N-((R)-1-Carbamimidoyl-piperidin-3-ylmethyl)-3...)
Affinity DataKi:  130nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  150nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037976({Benzyl-[(S)-3-[((S)-1-carbamimidoyl-piperidin-3-y...)
Affinity DataKi:  150nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL537204 | CHEMBL20...)
Affinity DataKi:  300nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037990({Butyl-[(S)-3-[((S)-1-carbamimidoyl-piperidin-3-yl...)
Affinity DataKi:  330nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKi:  360nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037989(N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-(naphth...)
Affinity DataKi:  480nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037999((S)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-3-(1H...)
Affinity DataKi:  660nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037994((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  780nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037983((2R,4R)-1-[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3...)
Affinity DataKi:  1.10E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037988(1-[(S)-3-[(1-Carbamimidoyl-piperidin-3-ylmethyl)-c...)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037991({[3-[(1-Carbamimidoyl-piperidin-3-ylmethyl)-carbam...)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037984({Butyl-[(S)-3-[((S)-1-carbamimidoyl-piperidin-3-yl...)
Affinity DataKi:  3.10E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037995({[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataKi:  3.80E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037980(1-[(S)-3-[(1-Carbamimidoyl-piperidin-3-ylmethyl)-c...)
Affinity DataKi:  5.40E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037993((S)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-4-mor...)
Affinity DataKi:  7.50E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037979({Benzyl-[(S)-3-[((S)-1-carbamimidoyl-piperidin-3-y...)
Affinity DataKi:  8.60E+3nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037974((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  1.20E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037992((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-3...)
Affinity DataKi:  1.70E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037972({[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataKi:  2.00E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037982((R)-3-(4-Acetylamino-phenyl)-N-(1-carbamimidoyl-pi...)
Affinity DataKi:  2.00E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037978({[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataKi:  2.30E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  2.60E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037999((S)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-3-(1H...)
Affinity DataKi:  2.70E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037985({[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataKi:  2.70E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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