Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50005533
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029623(1-chloro-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...)
Affinity DataIC50: 3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029625(4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1...)
Affinity DataIC50: 3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029613(1-methoxy-4-[2-(4-methylsulfonylphenyl)-1-cyclopen...)
Affinity DataIC50: 5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037941(1-chloro-4-{4,4-dimethyl-2-[4-(methylsulfonyl)phen...)
Affinity DataIC50: 7nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 10nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50: 15nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)
Affinity DataIC50: 26nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037942(1-[4,4-di(fluoromethyl)-2-(4-methylsulfonylphenyl)...)
Affinity DataIC50: 51nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037951(2,4-Dichloro-1-[2-(4-methanesulfonyl-phenyl)-cyclo...)
Affinity DataIC50: 53nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037950(1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-bis(t...)
Affinity DataIC50: 67nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037940(4-[2-(4-fluoro-2-methylphenyl)cyclopent-1-en-1-yl]...)
Affinity DataIC50: 75nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029616(5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...)
Affinity DataIC50: 90nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 200nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037946(1-(methylsulfonyl)-4-{2-[4-(methylthio)phenyl]cycl...)
Affinity DataIC50: 221nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029610(4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1...)
Affinity DataIC50: 865nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.20E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037941(1-chloro-4-{4,4-dimethyl-2-[4-(methylsulfonyl)phen...)
Affinity DataIC50: 1.60E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037943(1-Methanesulfonyl-4-(2-phenyl-cyclopent-1-enyl)-be...)
Affinity DataIC50: 2.25E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037949({4-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]...)
Affinity DataIC50: 3.20E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037947(1-(methoxymethyl)-4-{2-[4-(methylsulfonyl)phenyl]c...)
Affinity DataIC50: 6.60E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029613(1-methoxy-4-[2-(4-methylsulfonylphenyl)-1-cyclopen...)
Affinity DataIC50: 9.92E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50: 1.83E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037942(1-[4,4-di(fluoromethyl)-2-(4-methylsulfonylphenyl)...)
Affinity DataIC50: 5.80E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037944(1-[4,4-diethyl-2-(4-methylsulfonylphenyl)-1-cyclop...)
Affinity DataIC50: 6.50E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037948(4-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]-...)
Affinity DataIC50: 7.79E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037943(1-Methanesulfonyl-4-(2-phenyl-cyclopent-1-enyl)-be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037951(2,4-Dichloro-1-[2-(4-methanesulfonyl-phenyl)-cyclo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029610(4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029616(5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029625(4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037947(1-(methoxymethyl)-4-{2-[4-(methylsulfonyl)phenyl]c...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037950(1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-bis(t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037946(1-(methylsulfonyl)-4-{2-[4-(methylthio)phenyl]cycl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037948(4-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037949({4-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037940(4-[2-(4-fluoro-2-methylphenyl)cyclopent-1-en-1-yl]...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029623(1-chloro-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037944(1-[4,4-diethyl-2-(4-methylsulfonylphenyl)-1-cyclop...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed