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Found
139
Enz. Inhib. hit(s) with all data for entry = 4886
Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM29568
([3H]-Minipress | [3H]-Furazosin | PRAZOSIN HYDROCH...)
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Affinity Data
Ki: 0.110nM
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
Histamine H1 receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Affinity Data
Ki: 0.170nM
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Date in BDB:
12/28/2011
Entry Details
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Target
Histamine H1 receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
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Affinity Data
Ki: 0.950nM
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Date in BDB:
12/28/2011
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM86231
(CAS_51-55-8 | NSC_3661 | Atropine,(-) | ATROPINE |...)
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Affinity Data
Ki: 1.96nM
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Date in BDB:
12/28/2011
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM21395
(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
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Affinity Data
Ki: 2.5nM
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Date in BDB:
12/28/2011
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Target
Alpha-2A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 3.60nM
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Date in BDB:
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Target
Histamine H1 receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50017666
(2-(p-bromo-alpha-(2-dimethylaminoethyl)benzyl)pyri...)
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Affinity Data
Ki: 6.06nM
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Date in BDB:
12/28/2011
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Target
Histamine H1 receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
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Affinity Data
Ki: 6.30nM
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Date in BDB:
12/28/2011
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
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Affinity Data
Ki: 9.60nM
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Date in BDB:
12/28/2011
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
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Affinity Data
Ki: 18nM
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Affinity Data
Ki: 23nM
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Affinity Data
Ki: 23.5nM
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
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Affinity Data
Ki: 24nM
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50073444
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
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Affinity Data
Ki: 25nM
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50069447
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-e...)
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Affinity Data
Ki: 26nM
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Affinity Data
Ki: 27nM
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50334150
(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
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Affinity Data
Ki: 29nM
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
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Affinity Data
Ki: 32nM
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Target Info
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Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82438
(NSC_40589 | CAS_52942-31-1 | Etoperidone)
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Affinity Data
Ki: 36nM
More data for this Ligand-Target Pair
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Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
Copy SMILES
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Affinity Data
Ki: 37nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Histamine H1 receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Copy SMILES
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Affinity Data
Ki: 37nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82438
(NSC_40589 | CAS_52942-31-1 | Etoperidone)
Copy SMILES
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Affinity Data
Ki: 38nM
More data for this Ligand-Target Pair
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Date in BDB:
12/28/2011
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
Copy SMILES
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Affinity Data
Ki: 41nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50073444
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Copy SMILES
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Affinity Data
Ki: 42nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Copy SMILES
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Affinity Data
Ki: 46nM
More data for this Ligand-Target Pair
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Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50069447
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-e...)
Copy SMILES
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Affinity Data
Ki: 48nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
Copy SMILES
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Affinity Data
Ki: 55nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Histamine H1 receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Copy SMILES
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Affinity Data
Ki: 60nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Copy SMILES
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Affinity Data
Ki: 66nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82437
(CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...)
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Affinity Data
Ki: 67nM
More data for this Ligand-Target Pair
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ChEBI
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50069447
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-e...)
Copy SMILES
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Affinity Data
Ki: 80nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82438
(NSC_40589 | CAS_52942-31-1 | Etoperidone)
Copy SMILES
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Affinity Data
Ki: 85nM
More data for this Ligand-Target Pair
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Date in BDB:
12/28/2011
Entry Details
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Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50073444
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Copy SMILES
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Affinity Data
Ki: 96nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Copy SMILES
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Affinity Data
Ki: 100nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82437
(CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...)
Copy SMILES
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Affinity Data
Ki: 100nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
PC cid
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM22416
(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
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Affinity Data
Ki: 108nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
12/28/2011
Entry Details
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Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50014247
((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...)
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Affinity Data
Ki: 130nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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In Depth
Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
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Ki: 150nM
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Date in BDB:
12/28/2011
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PubMed
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50014247
((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...)
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Affinity Data
Ki: 184nM
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Date in BDB:
12/28/2011
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82437
(CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...)
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Ki: 200nM
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Date in BDB:
12/28/2011
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PubMed
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Target
5-hydroxytryptamine receptor 1A
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Ki: 276nM
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Date in BDB:
12/28/2011
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM30130
(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
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Ki: 280nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 1A
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM112777
(NORTRIPTYLINE | US8629135, SW-02)
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Ki: 294nM
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Date in BDB:
12/28/2011
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Target
Alpha-2A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50073444
(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
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Ki: 320nM
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Date in BDB:
12/28/2011
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM35229
(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
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Ki: 350nM
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Date in BDB:
12/28/2011
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PubMed
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Target
D(2) dopamine receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50079527
(CHEMBL101740 | cis-doxepin | DOXEPIN | (3E)-3-dibe...)
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Ki: 360nM
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Date in BDB:
12/28/2011
Entry Details
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PubMed
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Target
Histamine H1 receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82437
(CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...)
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Ki: 360nM
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Date in BDB:
12/28/2011
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82217
([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
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Ki: 380nM
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CHEMBL
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PC sid
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Date in BDB:
12/28/2011
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 1A
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
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Ki: 450nM
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Date in BDB:
12/28/2011
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Mayo Clinic
Curated by
PDSP K
i
Database
Ligand
BDBM82438
(NSC_40589 | CAS_52942-31-1 | Etoperidone)
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Ki: 570nM
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Date in BDB:
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