Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50005298
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035373(7-Chloro-2-(4-methoxy-phenyl)-3,5-dihydro-2H-pyraz...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035367(7-Chloro-2-phenyl-3,5-dihydro-2H-pyrazolo[3,4-c]qu...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035374(2-(4-Methoxy-phenyl)-3,5-dihydro-2H-pyrazolo[3,4-c...)
Affinity DataIC50: 87nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035370(3-Methyl-2-phenyl-3,5-dihydro-2H-pyrazolo[3,4-c]qu...)
Affinity DataIC50: 100nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035375(2-Phenyl-3,5-dihydro-2H-pyrazolo[3,4-c]quinoline-1...)
Affinity DataIC50: 135nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035372(2-(4-Chloro-phenyl)-3,5-dihydro-2H-pyrazolo[3,4-c]...)
Affinity DataIC50: 138nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035371(2-(3-Chloro-phenyl)-3,5-dihydro-2H-pyrazolo[3,4-c]...)
Affinity DataIC50: 162nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035369(2-Benzyl-3,5-dihydro-2H-pyrazolo[3,4-c]quinoline-1...)
Affinity DataIC50: 562nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035368(2-(2-Chloro-phenyl)-3,5-dihydro-2H-pyrazolo[3,4-c]...)
Affinity DataIC50: 613nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035376(2-Methyl-3,5-dihydro-2H-pyrazolo[3,4-c]quinoline-1...)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed