Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50005168
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033728(Pent-4-enoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033725(Propionic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033741(1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033737(3-Methyl-but-2-enoic acid (R)-1-(5,8-dihydroxy-1,4...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033735((E)-Pent-2-enoic acid (R)-1-(5,8-dihydroxy-1,4-dio...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033722(CHEMBL9416 | Isobutyric acid (R)-1-(5,8-dihydroxy-...)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033721(Trichloro-acetic acid (R)-1-(5,8-dihydroxy-1,4-dio...)
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033717((E)-Hepta-2,6-dienoic acid (R)-1-(5,8-dihydroxy-1,...)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 1.27E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033715((2E,4E)-Hexa-2,4-dienoic acid (R)-1-(5,8-dihydroxy...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033711(Chloro-acetic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-...)
Affinity DataIC50: 1.37E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033739(Butyric acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-di...)
Affinity DataIC50: 1.44E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033716((E)-Hex-2-enoic acid (R)-1-(5,8-dihydroxy-1,4-diox...)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033719((E)-Hex-3-enoic acid (R)-1-(5,8-dihydroxy-1,4-diox...)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033710((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033733(Pentanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 1.61E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033714(Hexanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-d...)
Affinity DataIC50: 2.07E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 2.08E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033732(Phenyl-acetic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-...)
Affinity DataIC50: 2.22E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033713(Hept-6-enoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033736(Octanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-d...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033740((E)-Octadec-9-enoic acid (R)-1-(5,8-dihydroxy-1,4-...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033724(Octadecanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033734((2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033730(Hexadecanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033729((9E,12E)-Octadeca-9,12-dienoic acid (R)-1-(5,8-dih...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033726((6E,9E,12E)-Octadeca-6,9,12-trienoic acid (R)-1-(5...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033727(Diphenyl-acetic acid (R)-1-(5,8-dihydroxy-1,4-diox...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033734((2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033723(Heptanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033720(Undecanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033718(Nonanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-d...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033712(Decanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-d...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033709(Dodecanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4...)
Affinity DataIC50: 6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed