Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50005041
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031845((4-Biphenyl-4-yl-1-phosphono-butyl)-phosphonic aci...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031839(((E)-6,10-Dimethyl-1-phosphono-undeca-5,9-dienyl)-...)
Affinity DataIC50: 1nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031843(((E)-8,12-Dimethyl-1-phosphono-trideca-7,11-dienyl...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031848(((E)-7,11-Dimethyl-1-phosphono-dodeca-6,10-dienyl)...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031844(((E)-1-Hydroxyphosphinoyl-6,10-dimethyl-undeca-5,9...)
Affinity DataIC50: 4nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031851(((E)-10,14-Dimethyl-1-phosphono-pentadeca-9,13-die...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031842([(5E,9E)-1-(Hydroxy-hydroxymethyl-phosphinoyl)-6,1...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031847(((5E,9E)-6,10,14-Trimethyl-1-phosphono-pentadeca-5...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031832([(6E,10E)-1-(Hydroxy-methyl-phosphinoyl)-7,11,15-t...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031859([(5E,9E)-1-(Hydroxy-methoxymethyl-phosphinoyl)-6,1...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031862([(E)-1-(Hydroxy-methyl-phosphinoyl)-10,14-dimethyl...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031836(((8E,12E)-9,13,17-Trimethyl-1-phosphono-octadeca-8...)
Affinity DataIC50: 11.8nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031849([(5E,9E)-1-(Hydroxy-methyl-phosphinoyl)-6,10,14-tr...)
Affinity DataIC50: 12.9nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031837([(E)-1-(Hydroxy-methoxymethyl-phosphinoyl)-6,10-di...)
Affinity DataIC50: 13.1nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031840([4-Biphenyl-4-yl-1-(hydroxy-methoxymethyl-phosphin...)
Affinity DataIC50: 14.8nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031854(((E)-9,13-Dimethyl-1-phosphono-tetradeca-8,12-dien...)
Affinity DataIC50: 17.6nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031855([4-Biphenyl-4-yl-1-(hydroxy-hydroxymethyl-phosphin...)
Affinity DataIC50: 23.9nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031850([(E)-1-(Hydroxy-methyl-phosphinoyl)-8,12-dimethyl-...)
Affinity DataIC50: 30.7nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031853(2E,6E-farnesyl bisphosphonate | ((3E,7E)-4,8,12-Tr...)
Affinity DataIC50: 32.4nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031846(((E)-4,8-Dimethyl-1-phosphono-nona-3,7-dienyl)-pho...)
Affinity DataIC50: 35.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031861([(E)-1-(Hydroxy-hydroxymethyl-phosphinoyl)-6,10-di...)
Affinity DataIC50: 38.7nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031841(((E)-5,9-Dimethyl-1-phosphono-deca-4,8-dienyl)-pho...)
Affinity DataIC50: 77.7nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031858([(E)-1-(Hydroxy-methyl-phosphinoyl)-6,10-dimethyl-...)
Affinity DataIC50: 81nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031834([(3E,7E)-1-(Hydroxy-methyl-phosphinoyl)-4,8,12-tri...)
Affinity DataIC50: 106nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031838([(E)-1-(Hydroxy-methyl-phosphinoyl)-9,13-dimethyl-...)
Affinity DataIC50: 374nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031863([4-Biphenyl-4-yl-1-(hydroxy-methyl-phosphinoyl)-bu...)
Affinity DataIC50: 490nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031856([(E)-1-(Hydroxy-methyl-phosphinoyl)-7,11-dimethyl-...)
Affinity DataIC50: 605nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031835((6E,10E)-7,11,15-Trimethyl-2-phosphono-hexadeca-6,...)
Affinity DataIC50: 880nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031833((E)-7,11-Dimethyl-2-phosphono-dodeca-6,10-dienoic ...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031857(5-Biphenyl-4-yl-2-phosphono-pentanoic acid | CHEMB...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031852((6-Methyl-1-phosphono-hept-5-enyl)-phosphonic acid...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031860([(E)-1-(Hydroxy-methyl-phosphinoyl)-4,8-dimethyl-n...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed