Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50034917
TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291167(1-((S)-Oxo-3-(R)-2-amino-1-phenyl-propyl)-pyrrolid...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291175(((R)-1-Benzyl-2-{(S)-2-[(R)-4-guanidino-1-(thiazol...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291175(((R)-1-Benzyl-2-{(S)-2-[(R)-4-guanidino-1-(thiazol...)
Affinity DataIC50: 2nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291173(1-((S)-2-Amino-3-(R)-phenyl-propionyl)-azetidine-2...)
Affinity DataIC50: 3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291167(1-((S)-Oxo-3-(R)-2-amino-1-phenyl-propyl)-pyrrolid...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProlyl endopeptidase(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)
Affinity DataIC50: 4.40nMAssay Description:The compound was tested for the inhibitory activity against prolyl endo peptidase(PEP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProlyl endopeptidase(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50291168((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 5nMAssay Description:The compound was tested for the inhibitory activity against prolyl endo peptidase(PEP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291166((R)-2-((R)-2-Amino-3-phenyl-propionylamino)-N-[(S)...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291173(1-((S)-2-Amino-3-(R)-phenyl-propionyl)-azetidine-2...)
Affinity DataIC50: 9nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291166((R)-2-((R)-2-Amino-3-phenyl-propionylamino)-N-[(S)...)
Affinity DataIC50: 180nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291172((S)-1-(3-Phenyl-propionyl)-pyrrolidine-2-carboxyli...)
Affinity DataIC50: 230nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291170((S)-1-((R)-2-Acetylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50: 230nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291171((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 230nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50118724((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataIC50: 260nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50038001(CHEMBL1166 | (2R,4S)-1-[5-Guanidino-2-(3-methyl-1,...)
Affinity DataIC50: 600nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291174((S)-1-((R)-2-Amino-3-phenyl-propionyl)-piperidine-...)
Affinity DataIC50: 730nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291172((S)-1-(3-Phenyl-propionyl)-pyrrolidine-2-carboxyli...)
Affinity DataIC50: 820nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50118724((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291171((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291170((S)-1-((R)-2-Acetylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291164((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProlyl endopeptidase(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50291169((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 7.70E+3nMAssay Description:The compound was tested for the inhibitory activity against prolyl endo peptidase(PEP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProlyl endopeptidase(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50291164((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 7.80E+3nMAssay Description:The compound was tested for the inhibitory activity against prolyl endo peptidase(PEP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291165((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291165((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProlyl endopeptidase(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50291171((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 2.80E+4nMAssay Description:The compound was tested for the inhibitory activity against prolyl endo peptidase(PEP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291174((S)-1-((R)-2-Amino-3-phenyl-propionyl)-piperidine-...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291164((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291168((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291169((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291169((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291168((S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carboxylic ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article