Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50034780
TargetAngiotensin-converting enzyme 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50017129(Vasotec | Vaseretic | (SSS)1-[2-(1-Ethoxycarbonyl-...)
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PDB3D3D Structure (crystal)
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283610((3S,5S)-4-(2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283612((3S,5R)-4-(2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283609((3S,5S)-4-(3-Biphenyl-4-yl-2-mercaptomethyl-propio...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAngiotensin-converting enzyme 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283613((2S,4S)-1-[(S)-2-((S)-1-Carboxy-3-phenyl-propylami...)
Affinity DataIC50: 42nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283611((3S,5S)-1-[2-((S)-(S)-1-Carboxy-3-phenyl-propylami...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283610((3S,5S)-4-(2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50: 87nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283608((3S,5S)-4-[3-(1-Mercaptomethyl-2-phenyl-ethyl)-ure...)
Affinity DataIC50: 118nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283608((3S,5S)-4-[3-(1-Mercaptomethyl-2-phenyl-ethyl)-ure...)
Affinity DataIC50: 147nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283613((2S,4S)-1-[(S)-2-((S)-1-Carboxy-3-phenyl-propylami...)
Affinity DataIC50: 149nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283606((2S,4R)-1-[(S)-2-((S)-1-Carboxy-3-phenyl-propylami...)
Affinity DataIC50: 253nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283605((3S,5R)-1-[2-((S)-(S)-1-Carboxy-3-phenyl-propylami...)
Affinity DataIC50: 506nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283609((3S,5S)-4-(3-Biphenyl-4-yl-2-mercaptomethyl-propio...)
Affinity DataIC50: 696nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283612((3S,5R)-4-(2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50: 849nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283606((2S,4R)-1-[(S)-2-((S)-1-Carboxy-3-phenyl-propylami...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283605((3S,5R)-1-[2-((S)-(S)-1-Carboxy-3-phenyl-propylami...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283611((3S,5S)-1-[2-((S)-(S)-1-Carboxy-3-phenyl-propylami...)
Affinity DataIC50: 1.24E+3nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283607(7-(2-Mercaptomethyl-3-phenyl-propionylamino)-hepta...)
Affinity DataKi:  26nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article