Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50034771
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282859((2S,4S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-pr...)
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282855((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282848(1-{2-[(S)-3-(2-Chloro-phenyl)-2-mercaptomethyl-pro...)
Affinity DataIC50: 2.20nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282845((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 2.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282851((S)-2-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 3.90nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282861((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50024101((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50: 5.70nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282852(1-[2-((S)-2-Mercaptomethyl-3-o-tolyl-propionylamin...)
Affinity DataIC50: 6.20nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282862((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50: 6.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282861((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 6.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282847((2S,4S)-4-Cyclohexyl-1-[(S)-2-((S)-2-mercaptomethy...)
Affinity DataIC50: 6.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282845((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 7.80nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282859((2S,4S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-pr...)
Affinity DataIC50: 8.70nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282858(3-((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-p...)
Affinity DataIC50: 9.40nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282855((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282846((S)-1-[(S)-3-(1H-Indol-3-yl)-2-((S)-2-mercaptometh...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282849(1-[2-(2-Mercaptomethyl-4-methyl-pentanoylamino)-pr...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282851((S)-2-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282847((2S,4S)-4-Cyclohexyl-1-[(S)-2-((S)-2-mercaptomethy...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282846((S)-1-[(S)-3-(1H-Indol-3-yl)-2-((S)-2-mercaptometh...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282848(1-{2-[(S)-3-(2-Chloro-phenyl)-2-mercaptomethyl-pro...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50048514((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282850((S)-1-[(S)-2-((2S,3S)-2-Benzyl-3-mercapto-butyryla...)
Affinity DataIC50: 32nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282862((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50: 37nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282844(1-{2-[3-(4-Benzyloxy-phenyl)-2-mercaptomethyl-prop...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282856((S)-1-[(S)-2-((R)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 45nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282852(1-[2-((S)-2-Mercaptomethyl-3-o-tolyl-propionylamin...)
Affinity DataIC50: 69nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282860((S)-1-[(S)-2-((2S,3R)-2-Benzyl-3-mercapto-butyryla...)
Affinity DataIC50: 78nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282853((S)-1-[(S)-2-((R)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50: 80nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282843((S)-2-((S)-2-Mercapto-3-phenyl-propionylamino)-4-m...)
Affinity DataIC50: 87nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50024101((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282857(1-[2-((S)-3-Mercapto-2-methyl-propionylamino)-prop...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282854(1-[2-(2-Mercaptomethyl-4-phenyl-butyrylamino)-prop...)
Affinity DataIC50: 160nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282860((S)-1-[(S)-2-((2S,3R)-2-Benzyl-3-mercapto-butyryla...)
Affinity DataIC50: 182nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282856((S)-1-[(S)-2-((R)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282853((S)-1-[(S)-2-((R)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50: 285nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282854(1-[2-(2-Mercaptomethyl-4-phenyl-butyrylamino)-prop...)
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50048514((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282850((S)-1-[(S)-2-((2S,3S)-2-Benzyl-3-mercapto-butyryla...)
Affinity DataIC50: 452nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282849(1-[2-(2-Mercaptomethyl-4-methyl-pentanoylamino)-pr...)
Affinity DataIC50: 490nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282844(1-{2-[3-(4-Benzyloxy-phenyl)-2-mercaptomethyl-prop...)
Affinity DataIC50: 880nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282843((S)-2-((S)-2-Mercapto-3-phenyl-propionylamino)-4-m...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282857(1-[2-((S)-3-Mercapto-2-methyl-propionylamino)-prop...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282858(3-((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-p...)
Affinity DataIC50: 3.20E+4nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50: 8.30E+5nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article