Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50034766
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282586(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(phosphonome...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282589(2-{(S)-2-[3-(4-Hydroxy-phenyl)-1-phosphono-propyla...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282588(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(3-phenyl-1-...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282593(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(3-naphthale...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282593(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(3-naphthale...)
Affinity DataIC50: 260nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282592(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(1-phosphono...)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282587(3-(S)-1H-Indol-3-yl-2-{(S)-2-[3-(1H-indol-3-yl)-1-...)
Affinity DataIC50: 560nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282595(PO3 2-Leu-Trp-O-3K | CHEMBL281562)
Affinity DataIC50: 960nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282588(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(3-phenyl-1-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282590(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(4-phenyl-1-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282585(PO3 2-Nle-Trp-O-3K | CHEMBL22509)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282587(3-(S)-1H-Indol-3-yl-2-{(S)-2-[3-(1H-indol-3-yl)-1-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282591(PO3 2-Ile-Trp-O-3K | CHEMBL281785)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282589(2-{(S)-2-[3-(4-Hydroxy-phenyl)-1-phosphono-propyla...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282586(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(phosphonome...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282590(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(4-phenyl-1-...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282594(PO3 2-Leu-Nal-O-3K | CHEMBL280917)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-converting enzyme 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50282592(3-(S)-1H-Indol-3-yl-2-[(S)-4-methyl-2-(1-phosphono...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Endothelin-converting enzyme (ECE) from microsomal fractions of bovine cultured endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails Article