Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50030066
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...)
Affinity DataIC50: 4nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta (PDGF beta-R)More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 70nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R) from NIH 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290838(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...)
Affinity DataIC50: 70nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 150nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R) in human aortic smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290836((3-Bromo-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-ami...)
Affinity DataIC50: 370nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290847(6,7-Dimethoxy-4-(3-methoxy-phenoxy)-quinoline | CH...)
Affinity DataIC50: 440nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290850(3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenol | CHEMBL...)
Affinity DataIC50: 560nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290837(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazolin...)
Affinity DataIC50: 570nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290848(6,7-Dimethoxy-4-(2-methoxy-phenoxy)-quinoline | CH...)
Affinity DataIC50: 600nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290844(6,7-Dimethoxy-4-(3-nitro-phenoxy)-quinoline | CHEM...)
Affinity DataIC50: 700nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290853(6,7-Dimethoxy-4-phenoxy-quinoline | CHEMBL327534)
Affinity DataIC50: 760nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290841(4-(3-Fluoro-phenoxy)-6,7-dimethoxy-quinoline | CHE...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290846(3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine | C...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290842(6,7-Dimethoxy-4-(4-methoxy-phenoxy)-quinoline | CH...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290839(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline | CHEM...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290849((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-y...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290835(CHEMBL100714 | CHEMBL544833 | (3,4-Dimethoxy-pheny...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290840(4-(2,3-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290835(CHEMBL100714 | CHEMBL544833 | (3,4-Dimethoxy-pheny...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290852(4-(3,5-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290845(6,7-Dimethoxy-4-m-tolyloxy-quinoline | CHEMBL98839)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290843(4-(3-Ethyl-phenoxy)-6,7-dimethoxy-quinoline | CHEM...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290839(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline | CHEM...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article

TargetCyclin-dependent kinase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cdc2More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Mitogen-activated protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPKKMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290851(4-(3-Ethoxy-phenoxy)-6,7-dimethoxy-quinoline | CHE...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290838(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290836((3-Bromo-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-ami...)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM3032(CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290854(4-(2,6-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 6.93E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In DepthDetails Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290849((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-y...)
Affinity DataIC50: 8.05E+4nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) in A431 cells.More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Fibroblast growth factor receptor in NIH 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290837(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazolin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In DepthDetails Article

TargetInsulin receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of insulin beta-R in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article