Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50029995
TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290071(N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  0.0592nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor kappa1 binding to guinea pig brain membranes, using 1 nM [3H]- U69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290076(N-[(S)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-...)
Affinity DataKi:  0.0855nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor kappa1 binding to guinea pig brain membranes, using 1 nM [3H]- U69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290072(5-{3-[3-((S)-1-{[2-(3,4-Dichloro-phenyl)-acetyl]-m...)
Affinity DataKi:  0.898nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor delta 1 binding to guinea pig brain membranes, using 0.2 nM [3H]naltrindole as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290072(5-{3-[3-((S)-1-{[2-(3,4-Dichloro-phenyl)-acetyl]-m...)
Affinity DataKi:  1.40nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor kappa1 binding to guinea pig brain membranes, using 1 nM [3H]- U69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290070(5-{3-[3-(1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methy...)
Affinity DataKi:  1.80nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor delta 1 binding to guinea pig brain membranes, using 0.2 nM [3H]naltrindole as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290071(N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  7.70nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor mu 1 binding to guinea pig brain membranes, using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290071(N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  7.80nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor delta 1 binding to guinea pig brain membranes, using 0.2 nM [3H]naltrindole as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290070(5-{3-[3-(1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methy...)
Affinity DataKi:  8.20nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor kappa1 binding to guinea pig brain membranes, using 1 nM [3H]- U69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290076(N-[(S)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-...)
Affinity DataKi:  8.40nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor mu 1 binding to guinea pig brain membranes, using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290076(N-[(S)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-...)
Affinity DataKi:  14nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor delta 1 binding to guinea pig brain membranes, using 0.2 nM [3H]naltrindole as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290074(N-[(R)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  15nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor kappa1 binding to guinea pig brain membranes, using 1 nM [3H]- U69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290075(N-[(R)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-...)
Affinity DataKi:  18nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor kappa1 binding to guinea pig brain membranes, using 1 nM [3H]- U69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290073(5-{3-[3-((R)-1-{[2-(3,4-Dichloro-phenyl)-acetyl]-m...)
Affinity DataKi:  86nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor delta 1 binding to guinea pig brain membranes, using 0.2 nM [3H]naltrindole as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290072(5-{3-[3-((S)-1-{[2-(3,4-Dichloro-phenyl)-acetyl]-m...)
Affinity DataKi:  98nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor mu 1 binding to guinea pig brain membranes, using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290073(5-{3-[3-((R)-1-{[2-(3,4-Dichloro-phenyl)-acetyl]-m...)
Affinity DataKi:  139nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor kappa1 binding to guinea pig brain membranes, using 1 nM [3H]- U69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290070(5-{3-[3-(1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methy...)
Affinity DataKi:  176nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor mu 1 binding to guinea pig brain membranes, using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290075(N-[(R)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-...)
Affinity DataKi:  1.04E+3nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor mu 1 binding to guinea pig brain membranes, using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290073(5-{3-[3-((R)-1-{[2-(3,4-Dichloro-phenyl)-acetyl]-m...)
Affinity DataKi:  1.19E+3nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor mu 1 binding to guinea pig brain membranes, using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290074(N-[(R)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  1.38E+3nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor mu 1 binding to guinea pig brain membranes, using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290074(N-[(R)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKi:  1.85E+3nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor delta 1 binding to guinea pig brain membranes, using 0.2 nM [3H]naltrindole as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290075(N-[(R)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-...)
Affinity DataKi:  3.07E+3nMAssay Description:Compound was evaluated for the inhibition of Opioid receptor delta 1 binding to guinea pig brain membranes, using 0.2 nM [3H]naltrindole as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article