Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50029736
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287416(2-Hydroxy-quinoline-4-carboxylic acid [(2R,4S)-2-b...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50000040(CHEMBL16192 | (+)(2-Benzhydryl-1-aza-bicyclo[2.2.2...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287400(2-[(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-ben...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287416(2-Hydroxy-quinoline-4-carboxylic acid [(2R,4S)-2-b...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287424([(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-benzo...)
Affinity DataIC50: 11nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287421(N-[(2R,4S)-2-Benzyl-1-(3,5-dimethyl-benzoyl)-piper...)
Affinity DataIC50: 12nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 13nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50000040(CHEMBL16192 | (+)(2-Benzhydryl-1-aza-bicyclo[2.2.2...)
Affinity DataIC50: 16nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287409({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 17nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287406({(2R,4S)-2-Benzyl-4-[(isoquinolin-3-ylmethyl)-amin...)
Affinity DataIC50: 19nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287402(N-[(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-ben...)
Affinity DataIC50: 19nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287405(1-[(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-ben...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287403({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 24nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287398({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 26nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287395({(2R,4S)-2-Benzyl-4-[(quinolin-3-ylmethyl)-amino]-...)
Affinity DataIC50: 30nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287395({(2R,4S)-2-Benzyl-4-[(quinolin-3-ylmethyl)-amino]-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]-SP radioligand binding to NK1 receptor from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287399(Quinoline-4-carboxylic acid [(2R,4S)-2-benzyl-1-(3...)
Affinity DataIC50: 48nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287399(Quinoline-4-carboxylic acid [(2R,4S)-2-benzyl-1-(3...)
Affinity DataIC50: 48nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287413({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 54nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 55nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287422(N-[(2R,4S)-2-Benzyl-1-(3,5-dichloro-benzoyl)-piper...)
Affinity DataIC50: 60nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287404(2-Amino-N-[(2R,4S)-2-benzyl-1-(3,5-bis-trifluorome...)
Affinity DataIC50: 62nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287415(1-[(2R,4S)-2-Benzyl-1-(3,5-dichloro-benzoyl)-piper...)
Affinity DataIC50: 72nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287428({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 92nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287412({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 110nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287417({(2S,4R)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 130nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287417({(2S,4R)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]-SP radioligand binding to NK1 receptor from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287411(((2R,4S)-4-Amino-2-benzyl-piperidin-1-yl)-(3,5-bis...)
Affinity DataIC50: 180nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287408({(2R,4S)-2-Benzyl-4-[(pyridin-4-ylmethyl)-amino]-p...)
Affinity DataIC50: 210nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287414(((2R,4S)-2-Benzyl-4-benzylamino-piperidin-1-yl)-(3...)
Affinity DataIC50: 220nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287418({(2S,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 220nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287420([(2R,4S)-2-Benzyl-4-(methyl-quinolin-4-ylmethyl-am...)
Affinity DataIC50: 390nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287416(2-Hydroxy-quinoline-4-carboxylic acid [(2R,4S)-2-b...)
Affinity DataIC50: 450nMAssay Description:Compound was tested for inhibition of [125I]eledoisin radioligand binding to NK3 receptor from gerbil cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287423({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 520nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287410({(2R,4R)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 540nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287396(N-[(2R,4S)-2-Benzyl-1-(3,5-dichloro-benzoyl)-piper...)
Affinity DataIC50: 600nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287429({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 700nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287426([(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-benzy...)
Affinity DataIC50: 880nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287425({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 1.04E+3nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287401({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 1.37E+3nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287419({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 1.38E+3nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 2.65E+3nMAssay Description:Compound was tested for inhibition of [125I]eledoisin radioligand binding to NK3 receptor from gerbil cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-K receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50287397({(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-...)
Affinity DataIC50: 2.79E+3nMAssay Description:Compound was tested for inhibition of [125I]NKA radioligand binding to NK2 receptor from bovine bladderMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287407(1-{(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino...)
Affinity DataIC50: 3.30E+3nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287399(Quinoline-4-carboxylic acid [(2R,4S)-2-benzyl-1-(3...)
Affinity DataIC50: 3.30E+3nMAssay Description:Compound was tested for inhibition of [125I]eledoisin radioligand binding to NK3 receptor from gerbil cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-K receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50287399(Quinoline-4-carboxylic acid [(2R,4S)-2-benzyl-1-(3...)
Affinity DataIC50: 4.50E+3nMAssay Description:Compound was tested for inhibition of [125I]NKA radioligand binding to NK2 receptor from bovine bladderMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287427([(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-benze...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287395({(2R,4S)-2-Benzyl-4-[(quinolin-3-ylmethyl)-amino]-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibition of [125I]eledoisin radioligand binding to NK3 receptor from gerbil cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article