Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50029730
TargetMu-type opioid receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50: 0.210nMAssay Description:Compound was tested for Inhibition of [3H]DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50: 0.530nMAssay Description:Compound was tested for Inhibition of 9 (1 nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMu-type opioid receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50287331(1N-[10-hydroxy-4-methyl-(13R,14R)-12-oxa-4-azapent...)
Affinity DataIC50: 0.560nMAssay Description:Compound was tested for Inhibition of [3H]DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50: 1.5nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMu-type opioid receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50287333(1N-[10-hydroxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50: 5.80nMAssay Description:Compound was tested for Inhibition of [3H]DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMu-type opioid receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50: 24nMAssay Description:Compound was tested for Inhibition of [3H]DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287331(1N-[10-hydroxy-4-methyl-(13R,14R)-12-oxa-4-azapent...)
Affinity DataIC50: 26nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287331(1N-[10-hydroxy-4-methyl-(13R,14R)-12-oxa-4-azapent...)
Affinity DataIC50: 45nMAssay Description:Compound was tested for Inhibition of 9 (1 nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50: 177nMAssay Description:Compound was tested for Inhibition of 9 (1 nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287333(1N-[10-hydroxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50: 178nMAssay Description:Compound was tested for Inhibition of 9 (1 nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287333(1N-[10-hydroxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50: 184nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50: 501nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article