Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50029616
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286220(2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50000041((+/-)(2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-...)
Affinity DataIC50: 0.600nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286216(2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50: 0.630nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50049468((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)
Affinity DataIC50: 0.870nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50052283(2-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286215(3-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286214(4-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286218([(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-p...)
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284632(3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-methyl-2-p...)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286217(2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286223(1-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286213([(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-p...)
Affinity DataIC50: 68nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286221([(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-p...)
Affinity DataIC50: 85nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286219((2S,3S)-1-Benzyl-3-(3,5-bis-trifluoromethyl-benzyl...)
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286222(2-[(2S,3S)-3-(2-Methoxy-benzylamino)-2-phenyl-pipe...)
Affinity DataIC50: 227nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50049468((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition of human Tachykinin receptor 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSubstance-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50049468((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition of human Neurokinin Tachykinin receptor 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article