Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50029556
Target5-hydroxytryptamine receptor 1D(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  8.5nMAssay Description:Compound was tested for the inhibition of forskolin-stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptor in guinea pig substantia nigraMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1D(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50285523([2-(5-Imidazo[4,5-b]pyridin-3-yl-1H-indol-3-yl)-et...)
Affinity DataEC50:  14nMAssay Description:Compound was tested for the inhibition of forskolin-stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptor in guinea pig substantia nigraMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1D(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50285522(CP-161242 | 1-[3-((R)-1-Methyl-pyrrolidin-2-ylmeth...)
Affinity DataEC50:  0.0420nMAssay Description:Compound was tested for the inhibition of forskolin-stimulated adenylate cyclase at 5-hydroxytryptamine 1D receptor in guinea pig substantia nigraMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  43nMAssay Description:Compound was tested for the inhibition of forskolin-stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285522(CP-161242 | 1-[3-((R)-1-Methyl-pyrrolidin-2-ylmeth...)
Affinity DataEC50:  26nMAssay Description:Compound was tested for the inhibition of forskolin-stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285523([2-(5-Imidazo[4,5-b]pyridin-3-yl-1H-indol-3-yl)-et...)
Affinity DataEC50:  460nMAssay Description:Compound was tested for the inhibition of forskolin-stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285522(CP-161242 | 1-[3-((R)-1-Methyl-pyrrolidin-2-ylmeth...)
Affinity DataIC50: 1.30nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]5-HT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 3nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]5-HT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 5.20nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1A receptor in rat cortex using [3H]OH-DPAT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285523([2-(5-Imidazo[4,5-b]pyridin-3-yl-1H-indol-3-yl)-et...)
Affinity DataIC50: 11nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]5-HT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50285522(CP-161242 | 1-[3-((R)-1-Methyl-pyrrolidin-2-ylmeth...)
Affinity DataIC50: 20nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1A receptor in rat cortex using [3H]OH-DPAT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50285523([2-(5-Imidazo[4,5-b]pyridin-3-yl-1H-indol-3-yl)-et...)
Affinity DataIC50: 210nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1A receptor in rat cortex using [3H]OH-DPAT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article